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This study evaluates the applicability of three thermal comfort indices—Physiologically Equivalent Temperature (PET), Standard Effective Temperature (SET), and Universal Thermal Climate Index (UTCI)—in various outdoor environments on the campus of Xi’an University, China. Meteorological data were collected on sunny days using a portable weather station at a height of 1.5 m, and subjective questionnaires were administered to 25 healthy university students over three months to gather Thermal Sensation Votes (TSV) and Thermal Comfort Votes (TCV). The study was conducted at four distinct outdoor locations: a lakeside area (Location 1), a shaded path (Location 2), a sports field (Location 3), and a plaza (Location 4). PET, SET, and UTCI values were calculated from the collected data using Rayman software. The analysis revealed significant differences in thermal comfort across the four locations, with the highest proportion of subjects feeling hot at the sports field (54.4%) and the highest proportion feeling cold at the lakeside (39%). The shaded path had the highest proportion of subjects feeling comfortable (79.4%), while the lakeside had the lowest (60.1%). The results indicated that SET underestimated thermal sensation at Locations 1, 3, and 4, necessitating calibration. PET was suitable for Locations 2, 3, and 4 but failed to reflect the thermal sensation at Location 1 due to prolonged sun exposure. In contrast, UTCI demonstrated applicability across all locations. To enhance accuracy, revised indices SET’ and PET’ were formulated using the mean-median method, providing more precise thermal comfort assessments. These findings underscore the limitations of SET and PET under specific conditions and highlight the robustness of UTCI, offering valuable insights for urban planning and design aimed at improving outdoor thermal comfort and well-being.

With the development trend of an aging society, Alzheimer’s disease (AD) has become an urgent problem in the field of medicine worldwide. Cognitive impairment in AD patients leads to a decline in the ability to perform daily living and abnormalities in behavior and personality, causing abnormal psychiatric symptoms, which seriously affect the daily life of patients. Currently, mainly drug therapy is used for AD patients in the clinic, but a large proportion of patients will experience drug efficacy not working, and even some drugs bring severe sleep disorders. Acupuncture, with its unique concept and treatment method, has been validated through a large number of experiments and proved its reliability of acupuncture in the treatment of AD. Many advances have been made in the study of the neurobiological mechanisms of acupuncture in the treatment of AD, further demonstrating the good efficacy and unique advantages of acupuncture in the treatment of AD. This review first summarizes the pathogenesis of AD and then illustrates the research progress of acupuncture in the treatment of AD, which includes the effect of acupuncture on the changes of biochemical indicators in AD in vivo and the specific mechanism of action to exert the therapeutic effect. Changes in relevant indicators of AD similarly further validate the effectiveness of acupuncture treatment. The clinical and mechanistic studies of acupuncture in the treatment of AD are intensified to fit the need for social development. It is believed that acupuncture will achieve new achievements in the treatment of AD as research progresses.

Fe-based amorphous/nanocrystalline soft magnetic alloys are widely used in high-tech fields such as communications and computers due to their advantages of high saturation magnetic induction, magnetic permeability, resistivity, low coercivity, and iron core loss. This article briefly introduces the preparation process of Fe-based amorphous alloys, highlights the classification and application of Fe-based amorphous/nanocrystalline materials, and the effects of various alloying elements on their organization and performance, and points out the Fe-based amorphous/nanocrystalline possible research trends of alloys.

The thalamus is an important sensory relay station. It integrates all somatic sensory pathways (excluding olfaction) and transmits information through thalamic relay neurons before projecting to the cerebral cortex via thalamocortical axons (TCAs). Emerging evidence has shown that FGF3, a member of the morphogen family, is an axon guidance molecule that repels TCAs away from the hypothalamus and into the internal capsule so that they subsequently reach different regions of the cortex. However, current studies on FGF-mediated axon guidance predominantly focus on phenomenological observations, with limited exploration of the underlying molecular mechanisms. To address this gap, we investigated both direct and indirect downstream signaling pathways mediating FGF3-dependent chemorepulsion of TCAs at later developmental stages. Firstly, we used pharmacological inhibitors to identify the signaling cascade(s) responsible for FGF3-triggered direct chemorepulsion of TCAs, in vitro and in vivo. Our results demonstrate that the PC-PLC pathway is required for FGF3 to directly stimulate the asymmetrical repellent growth of developing TCAs. Then, we found the FGF3-mediated repulsion can be indirectly induced by Slit1 because the addition of FGF3 in the culture media induced an increase in Slit1 expression in the diencephalon. Furthermore, by using downstream inhibitors, we found that the indirect repulsive effect of FGF3 is mediated through the PI3K downstream pathway of FGFR1.

In various ecosystems and human societies, living organisms and systems often exhibit cooperative and synchronous behaviors during survival. Recently, co-evolutionary models of cooperation and synchronization have shed light on the underlying mechanisms driving such behaviors, offering an intriguing avenue for studying these phenomena. However, current research predominantly focuses on a point-strategy decision mode, where each individual is limited to taking the same actions towards its neighbors. Such an assumption implies that an individual is unable to differentiate its neighbors and adjust its strategy accordingly, making it difficult to capture the complexity and diversity of interactive behaviors observed in reality. To this end, we introduce the interaction mode based on the edge-strategy and investigate how synchronization and cooperation co-evolve under interaction diversity. Specifically, we explore a scenario in which individuals can adopt different strategic decisions toward their neighbors based on their differences, thereby extending the traditional point strategy. Our research clarifies the positive role of interaction diversity in alleviating the evolutionary Kuramoto’s dilemma. Moreover, it provides new insights and ideas for comprehending the influence of edge-strategy on the co-evolution of cooperative and synchronous behaviors.

Objective To investigate the value of 7E instructional model in the teaching of nursing students in nursing clinical probation. Methods One hundred and fifty-nine nursing undergraduates of the class of 2018 who were on probation in our hospital from November 2020 to June 2021 were selected as the control group by convenience sampling, and the traditional teaching model was adopted; an additional 171 nursing undergraduates of the class of 2019 who were on clinical probation in the same hospital from November 2021 to June 2022 were selected as the experimental group, and the 7E instructional model was adopted, including elicit, engagement, exploration, explain, elaborate, evaluate and extend. Results After the intervention, the experimental group was higher than the control group in theoretical knowledge scores (59.47 ± 4.51 VS 54.11 ± 8.46), practical skills scores (19.62 ± 1.36 VS 19.14 ± 1.24) and total course scores (90.13 ± 2.98 VS 84.67 ± 4.47); total scores of learning motivation (30.57 ± 5.24 VS 29.41 ± 4.77), learning cooperation ability (20.35 ± 4.41 VS 19.02 ± 4.25), information literacy (23.14 ± 4.36 VS 21.12 ± 3.95) and self-regulated learning ability (114.00 ± 19.72 VS 109.07 ± 18.61); total scores of viewpoint acquisition (43.58 ± 5.21 VS 42.16 ± 5.10), emotional care (33.41 ± 4.54 VS 32.09 ± 4.47), transposition thinking (13.04 ± 2.97 VS 11.56 ± 2.43) and empathy ability (89.03 ± 13.87 VS 85.81 ± 13.55); and total scores of positive attitudes toward communication skills (55.39 ± 7.03 VS 51.54 ± 6.54), with a statistically significant difference ( P  < 0.05). Conclusion The 7E instructional model contributes to improved course grades, self-regulated learning and empathy, and positive attitudes toward communication skills among nursing students in their nursing clinical probation.

The utilization of hydrogen-enriched liquefied petroleum gas (LPG) is an effective means of reducing carbon emissions, but the special physical and chemical properties of hydrogen have raised concerns among the public. To delve into the intricate chemical kinetic mechanisms governing the inhibitory effect of CO2 on the explosion of hydrogen-enriched LPG, this study systematically investigated the influence of varying CO2 concentrations (3%, 6%, and 9%) on the explosion characteristics of hydrogen-enriched LPG (hydrogen ratio ranging from 0 to 0.5) within a 20 L spherical explosion chamber. Subsequently, a chemical kinetic analysis was conducted, focusing on the explosion reaction dynamics of the H2/LPG/CO2/Air mixture, encompassing temperature sensitivity assessments and the production rates of key free radicals. The findings reveal that although hydrogen incorporation does not significantly alter the maximum explosion pressure of LPG, it markedly accelerates the explosion reaction rate, posing a challenge for CO2 in effectively inhibiting the explosion of hydrogen-enriched LPG. CO2 functions as a stabilizing third body within the reaction system, diminishing the collision frequency among free radicals, hydrogen molecules, hydrocarbon molecules, and oxygen molecules, thereby slowing down the reaction rate. As the proportion of hydrogen increases, the concentration of ·H radicals, known for their high reactivity, escalates, rapidly completing the propagation phase of the chain reaction and intensifying the overall generation rates of critical free radicals, including ·H, ·O, and ·OH. Notably, the key reaction H+O2⇋O+OH, which governs the reaction temperature, undergoes significant enhancement, further accelerating the explosion reaction rate and ultimately diminishing the inhibitory efficacy of CO2 against the hydrogenated LPG explosion. Furthermore, as the amount of hydrogen added increases, hydrogen’s competitiveness for oxygen within the reaction system markedly improves, attenuating the oxidation of hydrocarbons. Concurrently, the alkane recombination reaction, exemplified by C3H6+CH3(+M)⇋sC4H9(+M), is strengthened. These insights provide valuable understanding of the complex interactions and mechanisms during the explosion of hydrogen-enriched LPG in the presence of CO2, with implications for the safe application of hydrogen-enriched LPG.

Resource integration of coal enterprises is conducive to reducing pollution and carbon emissions, thus alleviating environmental problems such as global warming. Government regulation has a great influence on enterprise behavior. Therefore, it is necessary to analyze the strategies of government and coal enterprises in resource integration. Based on the perspective of government regulation, this paper discusses how to guide and restrict coal enterprises to conduct resource integration behavior, and whether the government supervises this behavior. First, through empirical research, government regulations of coal enterprises are given practical policy implications. Second, using evolutionary game and simulation technology, from the perspective of government regulation, we explore the complex behavioral interaction mechanism between the dominant and inferior coal enterprises, the mechanism between the government and coal enterprises, and analyze the impact of key factors on the dynamic evolution process. Finally, the sensitivity analysis of the selected parameters is discussed in details, which provides useful decision-making suggestions for the government and enterprises. In addition, this paper further analyzes the impact of different government policies on coal enterprises' green innovation strategies. Results demonstrate that (1) when the power gap between enterprises is large, the probability of dominant enterprises choosing resource integration converges to 1, while the probability of inferior enterprises converges to 0. Therefore, government regulations are invalid for inferior enterprises; (2) the combination of government regulations can help improve the efficiency of coal enterprises’ strategic choices. With the increase in the intensity of government rewards and punishments, the probability of enterprise resource integration evolves from 0 to 1; (3) excessive government regulations make the choice between the government and coal companies tend to swing, because the probability of the two is between 0 and 1. Therefore, excessive government regulations cannot effectively achieve resource integration and government regulation. (4) The government subsidy strategy is less effective than the government’s pollution penalty strategy in promoting the green innovation of enterprises. Our research shows that the government should choose different policy combinations and intensities to regulate resource integration according to the market power of coal enterprises, which provides theoretical reference and practical guidance for the government to regulate corporate resource integration behavior.

The micro-arc oxidation of aluminum alloy is a kind of surface treatment technology for in-situ growth of a hard ceramic film with Al2O3 as the main effect of instantaneous high temperature and high pressure generated by arc discharge on the surface of aluminum alloy. This technology can significantly improve the wear resistance, corrosion resistance, hardness and other properties of the aluminum alloy matrix. This paper introduces the characteristics, influencing factors, research status of domestic and foreign micro-arc oxidation technology, and prospects for future research directions.

The role of education in a countrys progress is crucial. It ensures the intellectual and human resources a country needs to grow. There has been a growing consensus in China that gaining a thorough understanding of advanced foreign theories and effective teaching is crucial to keeping up with the country's rapid advancement and growth of its higher education system and the continuous intensifying and improved performance of the reform of education and teaching activities. College and university music programs often include piano teaching (PT) as a required curriculum component. As a result, the job it does in the classroom is crucial to developing modem musical literacy and understanding.. This article shows how to regulate the classroom tempo by utilizing multimedia instractional tools, how to pique students' interest in learning, and how to use multimedia tools to improve the quality of piano instruction. We used a logic programming system to design a piano teaching platform.it is used to analyze the knowledge of piano learners and manipulate their interference. By gathering user behavior from different Internet distribution platforms and evaluating the feature vector by the function space created by the pertinent evaluation metrics, the analysis system is also utilized to assess some instructional techniques' online public thought assessment. The system's accuracy is 96%, indicating a successful teaching assessment. The system's value evaluation paradigm makes it possible to comprehend user behaviors precisely and apply them to other disciplines.