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result(s) for
"Gray, Leon, author"
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Novavax NVX-COV2373 triggers neutralization of Omicron sub-lineages
by
Kaldine, Haajira
,
Lambson, Bronwen E.
,
Bennett, Chijioke
in
631/250/255
,
631/326/590
,
631/326/596/4130
2023
The SARS-CoV-2 Omicron (B.1.1.529) Variant of Concern (VOC) and its sub-lineages (including BA.2, BA.4, BA.5, BA.2.12.1) contain spike mutations that confer high level resistance to neutralizing antibodies induced by vaccination with ancestral spike or infection with previously circulating variants. The NVX-CoV2373 vaccine, a protein nanoparticle vaccine containing the ancestral spike sequence, has value in countries with constrained cold-chain requirements. Here we report neutralizing titers following two or three doses of NVX-CoV2373. We show that after two doses, Omicron sub-lineages BA.1 and BA.4/BA.5 were resistant to neutralization by 72% (21/29) and 59% (17/29) of samples respectively. However, after a third dose of NVX-CoV2373, we observed high titers against Omicron BA.1 (GMT: 1,197) and BA.4/BA.5 (GMT: 582), with responses similar in magnitude to those triggered by three doses of an mRNA vaccine. These data are of particular relevance as BA.4/BA.5 is dominating in multiple locations, and highlight the potential utility of the NVX-CoV2373 vaccine as a booster in resource-limited environments.
Journal Article
Cybercrime
by
Gray, Leon, 1974- author
in
Computer crimes Juvenile literature.
,
Computer crimes Investigation Juvenile literature.
,
Computer crimes.
2014
Explains the many areas of cybercrime, including worms, viruses, fraud, hacking, and cyberbullying.
Dirty bombs and shell shock : biology goes to war
by
Gray, Leon, 1974- author
in
Medicine, Military Juvenile literature.
,
Biological warfare Juvenile literature.
,
Medicine, Military.
2018
\"From using horses in battle to operating hospitals in a war zone, biology has been an important part of warfare. Readers will learn about the scientists and concepts that contributed to modern understanding of biology.\"--Provided by publisher.
How does a touch screen work?
by
Gray, Leon, 1974- author
in
Touch screens Juvenile literature.
,
Technological innovations Juvenile literature.
,
Touch screens.
2014
\"Readers will find out how layers of glass, metal, and LEDs work together to make a touch screen work. Full-color images augment explanations of different kinds of touch screens.\"-- Publisher's website.
Rivers and lakes
by
Gray, Leon, 1974- author
in
Rivers Juvenile literature.
,
Lakes Juvenile literature.
,
Freshwater ecology Juvenile literature.
2015
This book looks at the world's rivers and lakes and how animals and plants have adapted to live in and around fresh water..
Electricity
by
Gray, Leon, 1974- author
,
Eason, Sarah, editor
,
Sanderson, Jennifer, editor
in
Electricity Juvenile literature.
,
Electric power Juvenile literature.
,
Electricity.
2014
Over the past few hundred years, the introduction of electricity has changed how people live all over the world so much so that many can t imagine life without it! The earliest experiments with electricity, like those done by Ben Franklin and William Gilbert, will fascinate readers as they learn the basics of electricity, from atoms to circuits. Exemplified by familiar situations and items, the main science content supplements what readers will encounter in the classroom, including history as well as future energy sources such as wind and solar power. Vivid photographs and additional fact boxes make learning about science simply electrifying!
Forces and motion
by
Gray, Leon, 1974- author
,
Eason, Sarah, editor
,
Sanderson, Jennifer, editor
in
Force and energy Juvenile literature.
,
Motion Juvenile literature.
,
Force and energy.
2014
Introduces the concepts of forces and motion, covering such topics as the different types of forces, how force and motion have been studied throughout history, the laws that govern them, and simple machines.