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371,083 result(s) for "In, Francis"
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An introduction to wavelet theory in finance
This book offers an introduction to wavelet theory and provides the essence of wavelet analysis — including Fourier analysis and spectral analysis; the maximum overlap discrete wavelet transform; wavelet variance, covariance, and correlation — in a unified and friendly manner. It aims to bridge the gap between theory and practice by presenting substantial applications of wavelets in economics and finance.
Aristocracy in America : from the sketch-book of a German nobleman
\"Francis J. Grund, a German emigrant, was one of the most influential journalists in America in the three decades preceding the Civil War. He also wrote several books, including Aristocracy in America (1839), a fictional, satiric travel memoir written in response to Alexis de Tocqueville's famous Democracy in America. However, Grund's political work and life have never been analyzed in depth. In his introduction to this long out-of-print work, Armin Mattes provides a thorough account of Grund's dynamic engagement in American political life, and brings to light many of Grund's reflections on American social and political life previously published only in German. Comparing Aristocracy in America with Tocqueville's Democracy in America, Mattes shows how Grund's work can expand our understanding of the emerging democratic political culture and society in the antebellum United States\"--Provided by publisher.
A Longer Look at the Asymmetric Dependence between Hedge Funds and the Equity Market
This paper reexamines, at a range of investment horizons, the asymmetric dependence between hedge fund returns and market returns. Given the current availability of hedge fund data, the joint distribution of longer-horizon returns is extracted from the dynamics of monthly returns using the filtered historical simulation; we then apply the method based on copula theory to uncover the dependence structure therein. While the direction of asymmetry remains unchanged, the magnitude of asymmetry is attenuated considerably as the investment horizon increases. Similar horizon effects also occur on the tail dependence. Our findings suggest that nonlinearity in hedge fund exposure to market risk is more short term in nature, and that hedge funds provide higher benefits of diversification, the longer the horizon.
إفريقيا : السلم والنزاع
ظل السلم مفهوما محيرا طوال معظم تاريخ أفريقيا بعد الحقبة الاستعمارية، وثبت أن السلم والتنمية أصعب وأعقد فى تحقيقهما مما تنبأ به المتفائلون الأفارقة فى الحقبة التى تلت الاستقلال مباشرة. لهذا الكتاب هدفان أساسيان أولهما تقديم فهم نقدى للمفاهيم الأساسية والآراء والتأويلات النظرية لدراسات السلم والنزاع فى أفريقيا، والهدف الآخر تقديم تفسير محدد للسلم والنزاع فى عرض موجز متطور، مع تركيز خاص على المقاربات المحلية الأفريقية للسلم وفض النزاعات والأمن والتنمية وبناء السلم.
The Hedge Ratio and the Empirical Relationship between the Stock and Futures Markets: A New Approach Using Wavelet Analysis
This paper examines the relationship between the stock and futures markets in terms of lead‐lag relationship, correlation, and the hedge ratio using wavelet analysis. Empirical results show that (1) there is a feedback relationship between the stock and futures markets regardless of time scales, (2) wavelet correlation between two markets varies over investment horizons but remains very high, and (3) hedge ratio and the effectiveness of hedging strategies increase as the wavelet time scale increases. Simulation for utility comparisons shows that hedging effectiveness depends not only on the time scale but also on the risk aversion coefficient of an individual investor.
لغة الحياة : الحمض النووي والثورة في الطب الشخصي : تعتمد حياتك على أسرار حمضك النووي فهل أنت مستعد لهذا الأمر ؟
لقد اجتاحت حياتنا ثورة علمية وطبية، ففي الولايات المتحدة وحدها يعاني ستة آلاف شخص أمراضا نادرة، يعزى معظمها إلى خلل جيني أو الجينات الخطأ. عمليا تحدث جميع الأمراض بسبب مكون وراثي. وقد أخذت أمراض كثيرة، مثل السكري والقلب والسرطان والأمراض العقلية والربو وداء المفاصل والزهايمر، تتكشف أسرارها من خلال الحمض النووي. وقد بدأت عائلات كثيرة من التي واجهت مشكلات عامة، وكادت تفقد الأمل، تكتشف عالما جديدا من المعرفة والعلاج والوقاية، أنت مدين لنفسك لتعرف عن حمضك النووي : كيف يعمل وما يكشف، وما مزايا هذه المعرفة الجديدة وحدودها .كما أن ال د. فرانسيس كولينز ، من الرواد الباحثين في علم الجينات. قضى 15 عاما مديرا للمعهد الوطني لبحوث الجينوم البشري، حيث قاد مشروع الجينوم البشري العالمي إلى نهاية ناجحة. وتقديرا لمساهماته الثورية في البحوث الجينية، حصل على وسام الحرية عام 2007 م، والوسام الوطني للعلوم عام 2009 م، وهو مدير معهد الصحة الوطني الأمريكي.
Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone
Giant cell tumor (GCT) of bone is a unique bone lesion that is characterized by an excessive number of multinucleated osteoclasts. GCT consists of neoplastic stromal cells, multinucleated osteoclasts and their precursors, thus serving as a naturally occurring human disease model for the study of osteoclastogenesis. It still remains unclear how stromal cells of GCT recruit osteoclast precursors. In the present study, we characterized the cellular components of GCT and confirmed the presence of CD14 +-monocytes/CD68 +-macrophages and CD34 +-hematopoetic stem cells that express CXCR4, a specific receptor for SDF-1; SDF-1 gene expression and presence of SDF-1 protein were confirmed by real time RT-PCR, in situ hybridization, and immunohistochemistry in the GCT tissue and cultured cells. SDF-1 was present at 25–50 ng/ml in the conditioned media from the GCT cultures, which is in the range of physiological chemotactic concentration. Migration of osteoclast precursors was 2.5-fold higher in response to GCT conditioned media compared to the control media; and migration was inhibited by an average of 36% with anti-SDF-1 neutralizing antibody or competing recombinant SDF-1. These results suggest that SDF-1 is one of the significant chemoattractant factors involved in the recruitment of hematopoietic osteoclast precursor cells during tumor-induced osteoclastogenesis.
صراع الرؤى : نزاع الهويات في السودان
يتناول كتاب (صراع الرؤى : نزاع الهويات في السودان) والذي قامه بتأليفه فرانسيس دينق في حوالي (520) صفحة من القطع المتوسط موضوع (الصراع الطائفي) مستعرضا المحتويات التالية : القسم الأول : خليفة القسم، القسم الثاني تطور الهويات، القسم الثالث : البحت عن الأمة، القسم الرابع : شمال-جنوب عالم مصر، القسم الخامس : البعد الخارجي، القسم السادس : واقع الأزمة.
Diagnostic Value and Limitations of Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography for Cartilaginous Tumors of Bone
BackgroundA variety of imaging modalities are currently used for the preoperative evaluation of cartilage tumors. Although the anatomic details of the lesions are demonstrated well on computerized tomography and magnetic resonance images, those studies yield little information about the biologic activity of the tumors. In this study, we investigated the glucose metabolism of cartilage tumors measured by positron emission tomography and its correlation with histopathologic grades.MethodsThirty-five biopsy-proven cartilaginous tumors in twenty-seven patients were studied with plain radiographs, bone-scanning, magnetic resonance imaging, and positron emission tomography. The glucose metabolism in these cartilaginous tumors was measured quantitatively by calculating the maximal standardized uptake value of the region of interest. This value was then correlated with histopathologic grade, tumor size, recurrence, and metastasis.ResultsThere were thirteen benign bone tumors, twelve grade-I chondrosarcomas, and ten high-grade (grade-II or III) chondrosarcomas. The mean maximal standard uptake values were 1.147 ± 0.751 in the benign tumors, 0.898 ± 0.908 in the grade-I chondrosarcomas, and 6.903 ± 5.581 in the high-grade chondrosarcomas. There was no significant difference in these values between the benign cartilage tumors and the grade-I chondrosarcomas (p > 0.05). However, there was a significant difference between the low-grade (benign and grade-I) and high-grade chondrosarcomas (p = 0.009). Metastasis, but not tumor size or recurrence, was associated with a higher standard uptake value (p = 0.031). Two large pelvic grade-I chondrosarcomas demonstrated no radioisotope uptake on bone-scanning or on positron emission tomography. Positron emission tomography demonstrated grade-II and III metastatic lesions in the lung and other anatomic locations. When the cutoff for the standardized uptake value was set at 2.3 for grade-II or III chondrosarcomas, the positive predictive value was 0.82 (95% confidence interval, 0.48 to 0.97) and the negative predictive value was 0.96 (95% confidence interval, 0.77 to 1.00).ConclusionsGrade-II and III chondrosarcomas have a higher glucose metabolism than do low-grade cartilage tumors. However, the measurement of glucose metabolism by positron emission tomography alone cannot distinguish between benign and grade-I malignant cartilaginous tumors. It is important to understand the advantages and disadvantages of imaging modalities for accurate interpretation of results. Although positron emission tomography has limitations, it may be useful for predicting high-grade chondrosarcomas.Level of EvidenceDiagnostic study, Level II-1 (development of diagnostic criteria on basis of consecutive patients [with universally applied reference “gold” standard]). See Instructions to Authors for a complete description of levels of evidence.