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"Iskander, Adel"
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Edward Said
Edward W. Said (1935–2003) ranks as one of the most preeminent public intellectuals of our time. Through his literary criticism, his advocacy for the Palestinian cause, and his groundbreaking book Orientalism, Said elegantly enriched public discourse by unsettling the status quo. This indispensable volume, the most comprehensive and wide-ranging resource on Edward Said’s life and work, spans his broad legacy both within and beyond the academy. The book brings together contributions from thirty-one luminaries—leading scholars, critics, writers, and activists—to engage Said’s provocative ideas. Their essays and interviews explore the key themes of emancipation and representation through the prisms of postcolonial theory, literature, music, philosophy, and cultural studies.
eBook
Egypt in Flux
No chapter in Egypt’s contemporary history has been more turbulent and unpredictable than the past three years. In a very short period of time, the Arab world’s most populous country has seen a transition from rule by an iron-fisted dictatorship to a populist uprising to military omnipotence to Islamist electoral victory to constitutional turmoil to societal polarization. Egypt’s iconic revolution has been neither victorious nor defeated. Egypt in Flux is a collection of essays on the political, social, economic, and cultural dimensions of change in the country’s ongoing revolutionary current. While written over a span of several years, the essays are timeless in the historical context they provide and their ability to chart the country's trajectory in the period ahead. From the conditions that precipitated the uprising and the eruption of national dissent to the derailing of the revolution, the author reflects on the pressing topics of the day while being mindful of the counterrevolutionary movements and the continuation of the unending uprising. From discussions about the illusion of fair and free elections, social inequities, and labor disparities to examinations of religion, sports, literature, and sexuality, the essays in this valuable and intellectually stimulating volume chart both the broad lines and the nuances of an unfinished revolution.
eBook
Pimozide Augmentation of Clozapine Inpatients with Schizophrenia and Schizoaffective Disorder Unresponsive to Clozapine Monotherapy
Despite its superior efficacy, clozapine is helpful in only a subset of patients with schizophrenia unresponsive to other antipsychotics. This lack of complete success has prompted the frequent use of various clozapine combination strategies despite a paucity of evidence from randomized controlled trials supporting their efficacy. Pimozide, a diphenylbutylpiperidine, possesses pharmacological and clinical properties distinct from other typical antipsychotics. An open-label trial of pimozide adjunctive treatment to clozapine provided promising pilot data in support of a larger controlled trial. Therefore, we conducted a double-blind, placebo-controlled, parallel-designed 12-week trial of pimozide adjunctive treatment added to ongoing optimal clozapine treatment in 53 patients with schizophrenia and schizoaffective disorder partially or completely unresponsive to clozapine monotherapy. An average dose of 6.48 mg/day of pimozide was found to be no better than placebo in combination with clozapine at reducing Positive and Negative Syndrome Scale total, positive, negative, and general psychopathology scores. There is no suggestion from this rigorously conducted trial to suggest that pimozide is an effective augmenting agent if an optimal clozapine trial is ineffective. However, given the lack of evidence to guide clinicians and patients when clozapine does not work well, more controlled trials of innovative strategies are warranted.
Journal Article
Edward Said: emancipation and representation
This indispensable volume, a comprehensive and wide-ranging resource on Edward Said's life and work, spans his broad legacy both within and beyond the academy. The book brings together contributions from 31 luminaries to engage Said's provocative ideas.
eBook
Pimozide Augmentation of Clozapine Inpatients with Schizophrenia and Schizoaffective Disorder Unresponsive to Clozapine Monotherapy
Despite its superior efficacy, clozapine is helpful in only a subset of patients with schizophrenia unresponsive to other antipsychotics. This lack of complete success has prompted the frequent use of various clozapine combination strategies despite a paucity of evidence from randomized controlled trials supporting their efficacy. Pimozide, a diphenylbutylpiperidine, possesses pharmacological and clinical properties distinct from other typical antipsychotics. An open-label trial of pimozide adjunctive treatment to clozapine provided promising pilot data in support of a larger controlled trial. Therefore, we conducted a double-blind, placebo-controlled, parallel-designed 12-week trial of pimozide adjunctive treatment added to ongoing optimal clozapine treatment in 53 patients with schizophrenia and schizoaffective disorder partially or completely unresponsive to clozapine monotherapy. An average dose of 6.48mg/day of pimozide was found to be no better than placebo in combination with clozapine at reducing Positive and Negative Syndrome Scale total, positive, negative, and general psychopathology scores. There is no suggestion from this rigorously conducted trial to suggest that pimozide is an effective augmenting agent if an optimal clozapine trial is ineffective. However, given the lack of evidence to guide clinicians and patients when clozapine does not work well, more controlled trials of innovative strategies are warranted.
Journal Article
A proactive management algorithm for self healing mobile ad hoc networks
The ability to proactively manage mobile ad-hoc network (MANET) devices is critical for supporting complex services such as quality of service (QoS), security and access control in these networks. This research focuses on the problem of managing high dynamic and resource constrained MANET environments through the introduction of a novel Proactive Management Algorithm (PMA) for self healing MANETs. PMA is based on the effective integration of autonomous, predictive and adaptive distributed management strategies. Proactive management is achieved through the distributed analysis of the current performance of the mobile nodes utilizing an optimistic discrete event simulation method, which is used to predict the mobile nodes' future status and execute a proactive fault tolerant management scheme. PMA takes advantage of distributed parallel processing, flexibility and intelligence of active packets to minimize the management overhead, while adapting to the highly dynamic and resource-constrained nature of MANETs. The performance of the proposed PMA is validated using analytical performance analysis and simulation based on Active Virtual Network Management Protocol. The simulation results demonstrate that PMA not only significantly reduces management control overhead but also substantially improves both the performance and the stability under highly dynamic and limited resource conditions, which are typical for military, disaster relief and civilian applications in MANET environments.
Dissertation