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"Thomas, Gavin, author"
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Bursting Out in Praise
The author draws on his own hard-earned wisdom for this series of reflections on spirituality and mental health. He covers a range of experiences including: upsides, downsides, recovery, balance, loving life and spirituality. Bringing together wisdom from psychology and spirituality, he acknowledges the enormous benefit of psychological tools for wellness as well as a spirituality that aims to tell a different story. Ignatian Spirituality is a consistent thread throughout that offers a psycho-spirituality of great depth and awareness. This is a gentle introduction to spirituality and mental health. The real-life examples show that there is no dividing line between mental illness and normality. Everyone is somewhere along the mental health continuum and God is with them every step of the way.
eBook
Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis
Bovine mastitis, an inflammatory disease of the mammary gland, is classified as subclinical or clinical. Circulating neutrophils are recruited to the udder to combat infection. We compared the transcriptomic profiles in circulating leukocytes between healthy cows and those with naturally occurring subclinical or clinical mastitis. Holstein Friesian dairy cows from six farms in EU countries were recruited. Based on milk somatic cell count and clinical records, cows were classified as healthy (n = 147), subclinically (n = 45) or clinically mastitic (n = 22). Circulating leukocyte RNA was sequenced with Illumina NextSeq single end reads (30 M). Differentially expressed genes (DEGs) between the groups were identified using CLC Genomics Workbench V21, followed by GO enrichment analysis. Both subclinical and clinical mastitis caused significant changes in the leukocyte transcriptome, with more intensive changes attributed to clinical mastitis. We detected 769 DEGs between clinical and healthy groups, 258 DEGs between subclinical and healthy groups and 193 DEGs between clinical and subclinical groups. Most DEGs were associated with cell killing and immune processes. Many upregulated DEGs in clinical mastitis encoded antimicrobial peptides (
AZU1, BCL3, CAMP, CATHL1, CATHL2, CATHL4,CATHL5, CATHL6, CCL1, CXCL2, CXCL13, DEFB1, DEFB10, DEFB4A, DEFB7, LCN2, PGLYRP1, PRTN3, PTX3, S100A8, S100A9, S100A12, SLC11A1, TF
and
LTF
) which were not upregulated in subclinical mastitis. The use of transcriptomic profiles has identified a much greater up-regulation of genes encoding antimicrobial peptides in circulating leukocytes of cows with naturally occurring clinical compared with subclinical mastitis. These could play a key role in combatting disease organisms.
Journal Article
Sustainable Development
With growing evidence of unsustainable use of the world's resources, such as hydrocarbon reserves, and related environmental pollution, as in alarming climate change predictions, sustainable development is arguablytheprominent issue of the 21st century. This volume gives a wide ranging introduction focusing on the arid Gulf region, where the challenges of sustainable development are starkly evident. The Gulf relies on non-renewable oil and gas exports to supply the world's insatiable CO2 emitting energy demands, and has built unsustainable conurbations with water supplies dependent on energy hungry desalination plants and deep aquifers pumped beyond natural replenishment rates.Sustainable Developmenthas an interdisciplinary focus, bringing together university faculty and government personnel from the Gulf, Europe, and North America -- including social and natural scientists, environmentalists and economists, architects and planners -- to discuss topics such as sustainable natural resource use and urbanization, industrial and technological development, economy and politics, history and geography.
eBook
The rough guide to Dubai
Offers detailed practical advice on what to see and do in Dubai, with listings of all the hottest places to stay, eat, drink and shop on all budgets. This title also brings you information on the developments to Dubai Marina and the Palm Jumeirah, as well as day-trips throughout the UAE, including Sharajah, Al Ain, the East Coast and Abu Dhabi.
Book
The rough guide to Cambodia
Explore Cambodia with the smartest and most engaging guidebook on the market. Rough Guides' expert authors have done all the hard work for you: seeking out the top guesthouses, sampling the tastiest Khmer food and scouring the coast for the best beaches. Whether you're shopping in Phnom Penh's Central Market, exploring the astonishing ruins of Angkor, or relaxing on a sunset river cruise in Kampot, this new edition of The Rough Guide to Cambodia will show you ideal places to sleep, eat, drink and shop along the way, with options to suit every budget. The guide is packed with stunning photography and colour-coded, easy-to-use maps, and written with our trademark mix of candour, humour and practical advice. Make the most of your trip with The Rough Guide to Cambodia.
Book