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"Yu, Hong"
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Networking China : the digital transformation of the Chinese economy
\"In recent years, China 's leaders have taken decisive action to transform information, communications, and technology (ICT) into the nation's next pillar industry. In Networking China , Yu Hong offers an overdue examination of that burgeoning sector's political economy. Hong focuses on how the state, in conjunction with market forces and class interests, is constructing and realigning its digitalized sector. State planners intend to build a more competitive ICT sector by modernizing the network infrastructure, corporatizing media-and-entertainment institutions, and by using ICT as a crosscutting catalyst for innovation, industrial modernization, and export upgrades. The goal: to end China's industrial and technological dependence upon foreign corporations while transforming itself into a global ICT leader. The project, though bright with possibilities, unleashes implications rife with contradiction and surprise. Hong analyzes the central role of information, communications, and culture in Chinese-style capitalism. She also argues that the state and elites have failed to challenge entrenched interests or redistribute power and resources, as promised. Instead, they prioritize information, communications, and culture as technological fixes to make pragmatic tradeoffs between economic growth and social justice\"-- Provided by publisher.
Book
Unconventional CN vacancies suppress iron-leaching in Prussian blue analogue pre-catalyst for boosted oxygen evolution catalysis
The incorporation of defects, such as vacancies, into functional materials could substantially tailor their intrinsic properties. Progress in vacancy chemistry has enabled advances in many technological applications, but creating new type of vacancies in existing material system remains a big challenge. We show here that ionized nitrogen plasma can break bonds of iron-carbon-nitrogen-nickel units in nickel-iron Prussian blue analogues, forming unconventional carbon-nitrogen vacancies. We study oxygen evolution reaction on the carbon-nitrogen vacancy-mediated Prussian blue analogues, which exhibit a low overpotential of 283 millivolts at 10 milliamperes per square centimeter in alkali, far exceeding that of original Prussian blue analogues and previously reported oxygen evolution catalysts with vacancies. We ascribe this enhancement to the in-situ generated nickel-iron oxy(hydroxide) active layer during oxygen evolution reaction, where the Fe leaching was significantly suppressed by the unconventional carbon-nitrogen vacancies. This work opens up opportunities for producing vacancy defects in nanomaterials for broad applications.
Defect-engineering offers a promising route to vary material properties and reactivities, although the achievable defect types are limited. Here, the authors introduced unusual CN-vacancies in Prussian blue analogue pre-catalysts that can limit Fe leaching and improve oxygen evolution performances.
Journal Article
Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis
We here report that
miR‐17‐92
cluster is a novel target for p53‐mediated transcriptional repression under hypoxia. We found the expression levels of
miR‐17‐92
cluster were reduced in hypoxia‐treated cells containing wild‐type p53, but were unchanged in hypoxia‐treated p53‐deficient cells. The repression of
miR‐17‐92
cluster under hypoxia is independent of c‐Myc. Luciferase reporter assays mapped the region responding to p53‐mediated repression to a p53‐binding site in the proximal region of the
miR‐17‐92
promoter. Chromatin immunoprecipitation (ChIP), Re‐ChIP and gel retardation assays revealed that the binding sites for p53‐ and the TATA‐binding protein (TBP) overlap within the
miR‐17‐92
promoter; these proteins were found to compete for binding. Finally, we show that pri‐
miR‐17‐92
expression correlated well with p53 status in colorectal carcinomas. Over‐express
miR‐17‐92
cluster markedly inhibits hypoxia‐induced apoptosis, whereas blocked miR‐17‐5p and miR‐20a sensitize the cells to hypoxia‐induced apoptosis. These data indicated that p53‐mediated repression of
miR‐17‐92
expression likely has an important function in hypoxia‐induced apoptosis, and thus further our understanding of the tumour suppressive function of p53.
Journal Article
UDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice
Grain size is an important component trait of grain yield, which is frequently threatened by abiotic stress. However, little is known about how grain yield and abiotic stress tolerance are regulated. Here, we characterize
GSA1
, a quantitative trait locus (QTL) regulating grain size and abiotic stress tolerance associated with metabolic flux redirection.
GSA1
encodes a UDP-glucosyltransferase, which exhibits glucosyltransferase activity toward flavonoids and monolignols.
GSA1
regulates grain size by modulating cell proliferation and expansion, which are regulated by flavonoid-mediated auxin levels and related gene expression. GSA1 is required for the redirection of metabolic flux from lignin biosynthesis to flavonoid biosynthesis under abiotic stress and the accumulation of flavonoid glycosides, which protect rice against abiotic stress.
GSA1
overexpression results in larger grains and enhanced abiotic stress tolerance. Our findings provide insights into the regulation of grain size and abiotic stress tolerance associated with metabolic flux redirection and a potential means to improve crops.
Increasing grain yield needs to be put in the context of environmental stress. Here, the authors reveal that a UDP-glucosyltransferase is associated with regulation of rice grain size, abiotic stress tolerance, flavonoid-mediated auxin signaling, and redirection of carbon flux to flavonoid glycosides synthesis.
Journal Article
Mass production of bulk artificial nacre with excellent mechanical properties
Various methods have been exploited to replicate nacre features into artificial structural materials with impressive structural and mechanical similarity. However, it is still very challenging to produce nacre-mimetics in three-dimensional bulk form, especially for further scale-up. Herein, we demonstrate that large-sized, three-dimensional bulk artificial nacre with comprehensive mimicry of the hierarchical structures and the toughening mechanisms of natural nacre can be facilely fabricated via a bottom-up assembly process based on laminating pre-fabricated two-dimensional nacre-mimetic films. By optimizing the hierarchical architecture from molecular level to macroscopic level, the mechanical performance of the artificial nacre is superior to that of natural nacre and many engineering materials. This bottom-up strategy has no size restriction or fundamental barrier for further scale-up, and can be easily extended to other material systems, opening an avenue for mass production of high-performance bulk nacre-mimetic structural materials in an efficient and cost-effective way for practical applications.
Artificial materials that replicate the mechanical properties of nacre represent important structural materials, but are difficult to produce in bulk. Here, the authors exploit the bottom-up assembly of 2D nacre-mimetic films to fabricate 3D bulk artificial nacre with an optimized architecture and excellent mechanical properties.
Journal Article
The impossible fairy tale : a novel
\"The Impossible Fairy Tale is the story of two unexceptional grade-school girls. Mia is \"lucky\"--she is spoiled by her mother and, as she explains, her two fathers. She gloats over her exotic imported color pencils and won't be denied a coveted sweater. Then there is the Child who, by contrast, is neither lucky nor unlucky. She makes so little impression that she seems not even to merit a name. At school, their fellow students, whether lucky or luckless or unlucky, seem consumed by an almost murderous rage. Adults are nearly invisible, and the society the children create on their own is marked by cruelty and soul-crushing hierarchies. Then, one day, the Child sneaks into the classroom after hours and adds ominous sentences to her classmates' notebooks. This sinister but initially inconsequential act unlocks a series of events that end in horrible violence. But that is not the end of this eerie, unpredictable novel. A teacher, who is also this book's author, wakes from an intense dream. When she arrives at her next class, she recognizes a student: the Child, who knows about the events of the novel's first half, which took place years before. The Impossible Fairy Tale is a fresh and terrifying exploration of the ethics of art making and of the stinging consequences of neglect.\" -- Publisher's website
Book
A multi-responsive healable supercapacitor
Self-healability is essential for supercapacitors to improve their reliability and lifespan when powering the electronics. However, the lack of a universal healing mechanism leads to low capacitive performance and unsatisfactory intelligence. Here, we demonstrate a multi-responsive healable supercapacitor with integrated configuration assembled from magnetic Fe
3
O
4
@Au/polyacrylamide (MFP) hydrogel-based electrodes and electrolyte and Ag nanowire films as current collectors. Beside a high mechanical strength, MFP hydrogel exhibits fast optical and magnetic healing properties arising from distinct photothermal and magneto-thermal triggered interfacial reconstructions. By growing electroactive polypyrrole nanoparticles into MFP framework as electrodes, the assembled supercapacitor exhibits triply-responsive healing performance under optical, electrical and magnetic stimuli. Notably, the device delivers a highest areal capacitance of 1264 mF cm
−2
among the reported healable supercapacitors and restores ~ 90% of initial capacitances over ten healing cycles. These prominent performance advantages along with the facile device-assembly method make this emerging supercapacitor highly potential in the next-generation electronics.
Self-healing property is important for supercapacitors when powering the electronics, but designing devices that possess a universal healing mechanism remains challenging. Here, the authors achieve an optically, electrically, and magnetically-responsive self-healing device with integrated configuration.
Journal Article