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العلوم والتكنولوجيا والتربية والتعليم في الصين
حقيقة إن التنافس الدولي حاليا هو التنافس بين مستويات التنمية التكنولوجية والأكفاء للدول العالمية، تم في الصين تحديد وتطبيق استراتيجية رامية للنهوض بالبلاد بالاعتماد على العلوم والتكنولوجيا بعد انتهاج سياسة الاصلاح والإنفتاح في سنة 1978، فتشهد الصين نجاحا كبيرا في مجال التربية التكنولوجية وتحرز إنجازات هامة متقدمة في العالم ؛ وفي الوقت نفسه، قد تأسس فيها أكبر هيكل التعليم القومي حجما في العالم، مما يقدم قاعدة راسخة وقوة محركة قوية لدعم التنمية الاقتصادية الاجتماعية والقوة الوطنية العامة والقوة التنافسية الدولية للصين.
BOOK
The Inhomogeneity Effect. I. Inhomogeneous Surface and Atmosphere Accelerate Planetary Cooling
We propose a general principle that under radiative-convective equilibrium, the spatial and temporal variations in a planet’s surface and atmosphere tend to increase its cooling. This principle is based on Jensen’s inequality and the curvature of the response functions of surface temperature and outgoing cooling flux to changes in incoming stellar flux and atmospheric opacity. We use an analytical model to demonstrate that this principle holds for various planet types: (1) on an airless planet, the mean surface temperature is lower than its equilibrium temperature; (2) on terrestrial planets with atmospheres, the inhomogeneity of incoming stellar flux and atmospheric opacity reduces the mean surface temperature; (3) on giant planets, inhomogeneously distributed stellar flux and atmospheric opacity increase the outgoing infrared flux, cooling the interior. Although the inhomogeneity of visible opacity might sometimes heat the atmosphere, the effect is generally much smaller than the inhomogeneous cooling effect of infrared opacity. Compared with the homogeneous case, the mean surface temperature on inhomogeneous terrestrial planets can decrease by more than 20%, and the internal heat flux on giant planets can increase by over an order of magnitude. Despite simplifications in our analytical framework, the effect of stellar flux inhomogeneity appears to be robust, while further research is needed to fully understand the effects of opacity inhomogeneity in more realistic situations. This principle impacts our understanding of planetary habitability and the evolution of giant planets using low-resolution and one-dimensional frameworks that may have previously overlooked the role of inhomogeneity.
Journal Article
The Inhomogeneity Effect. II. Rotational and Orbital States Impact Planetary Cooling
We generalize the theory of the inhomogeneity effect to enable comparison among different inhomogeneous planets. A metric of inhomogeneity based on the cumulative distribution function is applied to investigate the dependence of planetary cooling on previously overlooked parameters. The mean surface temperature of airless planets increases with rotational rate and surface thermal inertia, which bounds the value in the tidally locked configuration and the equilibrium temperature. Using an analytical model, we demonstrate that the internal heat flux of giant planets exhibits significant spatial variability, primarily emitted from the nightside and high-latitude regions acting as radiator fins. Given a horizontally uniform interior temperature in the convective zone, the outgoing internal flux increases up to several folds as the inhomogeneity of the incoming stellar flux increases. The enhancement decreases with increasing heat redistribution through planetary dynamics or rotation. The outgoing internal flux on rapidly rotating planets generally increases with planetary obliquity and orbital eccentricity. The radiative timescale and true anomaly of the vernal equinox also play significant roles. If the radiative timescale is long, the outgoing internal flux shows a slightly decreasing but nonlinear trend with obliquity. Our findings indicate that rotational and orbital states greatly influence the cooling of planets and impact the interior evolution of giant planets, particularly for tidally locked planets and planets with high eccentricity and obliquity (such as Uranus), as well as the spatial and temporal variations of their cooling fluxes.
Journal Article
Spin-momentum locking and spin-orbit torques in magnetic nano-heterojunctions composed of Weyl semimetal WTe2
Spin–orbit torque has recently been intensively investigated for the purposes of manipulating the magnetization in magnetic nano-devices and understanding fundamental physics. Therefore, the search for novel materials or material combinations that exhibit a strong enough spin-torque effect has become one of the top priorities in this field of spintronics. Weyl semimetal, a new topological material that features open Fermi arc with strong spin–orbit coupling and spin–momentum locking effect, is naturally expected to exhibit an enhanced spin-torque effect in magnetic nano-devices. Here we observe a significantly enhanced spin conductivity, which is associated with the field-like torque at low temperatures. The enhancement is obtained in the
b
-axis WTe
2
/Py bilayers of nano-devices but not observed in the
a
-axis of WTe
2
/Py nano-devices, which can be ascribed to the enhanced spin accumulation by the spin–momentum locking effect of the Fermi arcs of the Weyl semimetal WTe
2
.
The Fermi arcs, topological surface states of Weyl semimetals can enable the intriguing spin control and facilitate topological spintronics. Here the authors report the spin-orbit torque at the interface of WTe
2
/Py and attribute it to the enhanced spin accumulation by the spin-momentum locking effect of the Fermi arcs of WTe
2
.
Journal Article
Evidence for topological type-II Weyl semimetal WTe2
Recently, a type-II Weyl fermion was theoretically predicted to appear at the contact of electron and hole Fermi surface pockets. A distinguishing feature of the surfaces of type-II Weyl semimetals is the existence of topological surface states, so-called Fermi arcs. Although WTe
2
was the first material suggested as a type-II Weyl semimetal, the direct observation of its tilting Weyl cone and Fermi arc has not yet been successful. Here, we show strong evidence that WTe
2
is a type-II Weyl semimetal by observing two unique transport properties simultaneously in one WTe
2
nanoribbon. The negative magnetoresistance induced by a chiral anomaly is quite anisotropic in WTe
2
nanoribbons, which is present in
b
-axis ribbon, but is absent in
a
-axis ribbon. An extra-quantum oscillation, arising from a Weyl orbit formed by the Fermi arc and bulk Landau levels, displays a two dimensional feature and decays as the thickness increases in WTe
2
nanoribbon.
Exotic transport properties of type-II Weyl semimetals have been predicted but are yet to be experimentally evidenced. Here, Li et al. report evidences of an anisotropy of negative magnetoresistance and a quantum oscillation arising from the predicted Weyl orbit in the type-II Weyl semimetal WTe
2
.
Journal Article
Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells
Zinc oxide nanoparticles (ZnO NPs) are frequently used in industrial products such as paint, surface coating, and cosmetics, and recently, they have been explored in biologic and biomedical applications. Therefore, this study was undertaken to investigate the effect of ZnO NPs on cytotoxicity, apoptosis, and autophagy in human ovarian cancer cells (SKOV3).
ZnO NPs with a crystalline size of 20 nm were characterized with various analytical techniques, including ultraviolet-visible spectroscopy, X-ray diffraction, transmission electron microscopy, Fourier transform infrared spectroscopy, and atomic force microscopy. The cytotoxicity, apoptosis, and autophagy were examined using a series of cellular assays.
Exposure of cells to ZnO NPs resulted in a dose-dependent loss of cell viability, and the characteristic apoptotic features such as rounding and loss of adherence, enhanced reactive oxygen species generation, and loss of mitochondrial membrane potential were observed in the ZnO NP-treated cells. Furthermore, the cells treated with ZnO NPs showed significant double-strand DNA breaks, which are gained evidences from significant number of γ-H
AX and Rad51 expressed cells. ZnO NP-treated cells showed upregulation of p53 and LC3, indicating that ZnO NPs are able to upregulate apoptosis and autophagy. Finally, the Western blot analysis revealed upregulation of Bax, caspase-9, Rad51, γ-H
AX, p53, and LC3 and downregulation of Bcl-2.
The study findings demonstrated that the ZnO NPs are able to induce significant cytotoxicity, apoptosis, and autophagy in human ovarian cells through reactive oxygen species generation and oxidative stress. Therefore, this study suggests that ZnO NPs are suitable and inherent anticancer agents due to their several favorable characteristic features including favorable band gap, electrostatic charge, surface chemistry, and potentiation of redox cycling cascades.
Journal Article
Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches
Recent advances in nanoscience and nanotechnology radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications. AgNPs play an important role in nanoscience and nanotechnology, particularly in nanomedicine. Although several noble metals have been used for various purposes, AgNPs have been focused on potential applications in cancer diagnosis and therapy. In this review, we discuss the synthesis of AgNPs using physical, chemical, and biological methods. We also discuss the properties of AgNPs and methods for their characterization. More importantly, we extensively discuss the multifunctional bio-applications of AgNPs; for example, as antibacterial, antifungal, antiviral, anti-inflammatory, anti-angiogenic, and anti-cancer agents, and the mechanism of the anti-cancer activity of AgNPs. In addition, we discuss therapeutic approaches and challenges for cancer therapy using AgNPs. Finally, we conclude by discussing the future perspective of AgNPs.
Journal Article
Electric-field-driven non-volatile multi-state switching of individual skyrmions in a multiferroic heterostructure
Electrical manipulation of skyrmions attracts considerable attention for its rich physics and promising applications. To date, such a manipulation is realized mainly via spin-polarized current based on spin-transfer torque or spin–orbital torque effect. However, this scheme is energy consuming and may produce massive Joule heating. To reduce energy dissipation and risk of heightened temperatures of skyrmion-based devices, an effective solution is to use electric field instead of current as stimulus. Here, we realize an electric-field manipulation of skyrmions in a nanostructured ferromagnetic/ferroelectrical heterostructure at room temperature via an inverse magneto-mechanical effect. Intriguingly, such a manipulation is non-volatile and exhibits a multistate feature. Numerical simulations indicate that the electric-field manipulation of skyrmions originates from strain-mediated modification of effective magnetic anisotropy and Dzyaloshinskii–Moriya interaction. Our results open a direction for constructing low-energy-dissipation, non-volatile, and multistate skyrmion-based spintronic devices.
Spin-polarized current manipulation of magnetic skyrmions is energy consuming. Here, the authors achieve an electric-field manipulation of individual skyrmions in a nanostructured ferromagnetic/ferroelectrical heterostructure at room temperature via an inverse magneto-mechanical effect.
Journal Article
Two-dimensional Models of Microphysical Clouds on Hot Jupiters. I. Cloud Properties
We present a new two-dimensional, bin-scheme microphysical model of cloud formation in the atmospheres of hot Jupiters that includes the effects of longitudinal gas and cloud transport. We predict cloud particle size distributions as a function of planetary longitude and atmospheric height for a grid of hot Jupiters with equilibrium temperatures ranging from 1000 to 2100 K. The predicted 2D cloud distributions vary significantly from models that do not consider horizontal cloud transport and we discuss the microphysical and transport timescales that give rise to the differences in 2D versus 1D models. We find that the horizontal advection of cloud particles increases the cloud formation efficiency for nearly all cloud species and homogenizes cloud distributions across the planets in our model grid. In 2D models, certain cloud species are able to be transported and survive on the daysides of hot Jupiters in cases where 1D models would not predict the existence of clouds. We demonstrate that the depletion of condensible gas species varies as a function of longitude and atmospheric height across the planet, which impacts the resultant gas-phase chemistry. Finally, we discuss various model sensitivities including the sensitivity of cloud properties to microphysical parameters, which we find to be substantially less than the sensitivity to the atmospheric thermal structure and horizontal and vertical transport of condensible material.
Journal Article
Silver Nanoparticle-Mediated Cellular Responses in Various Cell Lines: An in Vitro Model
Silver nanoparticles (AgNPs) have attracted increased interest and are currently used in various industries including medicine, cosmetics, textiles, electronics, and pharmaceuticals, owing to their unique physical and chemical properties, particularly as antimicrobial and anticancer agents. Recently, several studies have reported both beneficial and toxic effects of AgNPs on various prokaryotic and eukaryotic systems. To develop nanoparticles for mediated therapy, several laboratories have used a variety of cell lines under in vitro conditions to evaluate the properties, mode of action, differential responses, and mechanisms of action of AgNPs. In vitro models are simple, cost-effective, rapid, and can be used to easily assess efficacy and performance. The cytotoxicity, genotoxicity, and biocompatibility of AgNPs depend on many factors such as size, shape, surface charge, surface coating, solubility, concentration, surface functionalization, distribution of particles, mode of entry, mode of action, growth media, exposure time, and cell type. Cellular responses to AgNPs are different in each cell type and depend on the physical and chemical nature of AgNPs. This review evaluates significant contributions to the literature on biological applications of AgNPs. It begins with an introduction to AgNPs, with particular attention to their overall impact on cellular effects. The main objective of this review is to elucidate the reasons for different cell types exhibiting differential responses to nanoparticles even when they possess similar size, shape, and other parameters. Firstly, we discuss the cellular effects of AgNPs on a variety of cell lines; Secondly, we discuss the mechanisms of action of AgNPs in various cellular systems, and try to elucidate how AgNPs interact with different mammalian cell lines and produce significant effects; Finally, we discuss the cellular activation of various signaling molecules in response to AgNPs, and conclude with future perspectives on research into AgNPs.
Journal Article