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"Psychotropic Drugs therapeutic use."
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Handbook of clinical psychopharmacology for therapists
\"The Handbook of Clinical Psychopharmacology for Therapists is the go-to resource for mental health clinicians looking for clear, reliable information about the treatment of mental health issues. Organized by disorder and, within each disorder, by medication, this book is designed to familiarize clinicians and students with the basic terminology and models of pharmacokinetics.This fully revised and updated eighth edition provides essential information on new medications and treatment options and includes the latest research on side effects, contraindications, and efficacy of all major medications prescribed for mental health disorders. The book also features an important new chapter on the effects of withdrawing from psychopharmacological medications.This handbook makes it simple to: get the facts about drug interactions and side effects; find out how medications affect adults, children, and adolescents differently; learn how different cultures view medical treatment; vital information for anyone who treats clients from a variety of backgrounds; and discontinue medication safely when needed.This essential guide to psychopharmacology has been adopted as a textbook at universities nationwide and is an important resource for every therapist's library\"-- Provided by publisher.
Prepandemic psychotropic drug status in Portugal: a nationwide pharmacoepidemiological profile
2023
The prescription of psychotropic drugs has been rising in Europe over the last decade. This study provides a comprehensive profile of prepandemic consumption patterns of antidepressant, antipsychotic, and anxiolytic drugs in Portugal considering full nationwide psychotropic drug prescription and dispensing records (2016–2019) against several criteria, including active ingredient, sociodemographics, medical specialty, and incurred costs. An increase of 29.6% and 34.7% in the consumption of antipsychotics and antidepressants between 2016 and 2019 is highlighted, accompanied by an increase of 37M Eur in total expenditure (> 20M Eur in public copay) for these classes of drugs. Disparities in sociodemographic and geographical incidence are identified. Amongst other pivotal results, 64% of psychotropic drug prescriptions are undertaken by general practitioners, while only 21% undertaken by neurological and psychiatric specialties. Nationwide patterns of psychotropic drug prescription further reveal notable trends and determinants, establishing a reference point for cross-regional studies and being currently assessed at a national level to establish psychosocial initiatives and guidelines for medical practice and training.
Journal Article
Happy pills in America : from Miltown to Prozac
2010,2009
Valium. Paxil. Prozac. Prescribed by the millions each year, these medications have been hailed as wonder drugs and vilified as numbing and addictive crutches. Where did this \"blockbuster drug\" phenomenon come from? What factors led to the mass acceptance of tranquilizers and antidepressants? And how has their widespread use affected American culture?
David Herzberg addresses these questions by tracing the rise of psychiatric medicines, from Miltown in the 1950s to Valium in the 1970s to Prozac in the 1990s. The result is more than a story of doctors and patients. From bare-knuckled marketing campaigns to political activism by feminists and antidrug warriors, the fate of psychopharmacology has been intimately wrapped up in the broader currents of modern American history. Beginning with the emergence of a medical marketplace for psychoactive drugs in the postwar consumer culture, Herzberg traces how \"happy pills\" became embroiled in Cold War gender battles and the explosive politics of the \"war against drugs\"—and how feminists brought the two issues together in a dramatic campaign against Valium addiction in the 1970s. A final look at antidepressants shows that even the Prozac phenomenon owed as much to commerce and culture as to scientific wizardry.
With a barrage of \"ask your doctor about\" advertisements competing for attention with shocking news of drug company malfeasance, Happy Pills is an invaluable look at how the commercialization of medicine has transformed American culture since the end of World War II.
The Maudsley prescribing guidelines in psychiatry
by
Taylor, David
,
Paton, Carol
,
South London and Maudsley NHS Trust
in
Drugs
,
Great Britain
,
Mental Disorders -- drug therapy -- Great Britain
2012
Helps with complex prescribing needs The evidence base for drug treatments in psychiatry ranges from meta-analyses and randomised controlled clinical trials to single case reports, and from NICE guidelines to individual SPCs. Where do you look for information when transferring a patient from one drug to another? Where do you find a clear overview when dealing with a complex patient (e.g, with co-morbid epilepsy or liver disease or HIV infection)? Where can you seek advice on prescribing psychotropics during pregnancy? The Maudsley Prescribing Guidelines in Psychiatry! The leading clinical reference for handling prescribing problems as encountered in daily practice and for formulating prescribing policy. Evidence-based and written by experts This book is the essential guide for anyone responsible for prescribing, dispensing or administering drugs for patients with mental health disorders. All the evidence has been reviewed and summarized succinctly by an expert team of psychiatrists and pharmacists. New content and improved format This new edition makes greater use of tables and boxes to facilitate quick reference and includes new sections on cytochrome-mediated interactions and psychiatric side effects of non-psychotropic drugs. Clinically relevant Chapters address plasma monitoring, schizophrenia, bipolar disorder, depression and anxiety, children and adolescents, substance abuse and special patient groups. Each section has a full reference list. The book covers prescribing drugs outside their licensed indications and their interaction with substances such as alcohol, nicotine and caffeine. Useful for all levels of experience Trainees will gain important information regarding the rational, safe and effective use of medications for patients with mental illness. Experienced clinicians will find excellent guidance regarding more complex issues that they may not encounter regularly. Why the Maudsley Prescribing Guidelines in Psychiatry? Long recognized as an international trailblazer in mental health care, the Maudsley Hospital earned its reputation for excellence in both in-patient and community care. It is highly regarded for its research, and pioneered the use of clinical neuroscience. You can trust The Maudsley Prescribing Guidelines in Psychiatry to be scientifically sound and clinically effective.
Principles and Practice of Psychopharmacotherapy
by
Marder, Stephen R
,
Janicak, Philip G
,
Pavuluri, Mani N
in
Chemotherapy
,
Mental illness
,
Psychopharmacology
2010,2011
Fully updated for its Fifth Edition, Principles and Practice of Psychopharmacotherapy summarizes the latest data on hundreds of drug and device-based therapies and offers practical, evidence-based guidelines and treatment strategies for virtually every psychiatric disorder. Highlights of this edition include expanded coverage of pharmacogenomics, updates on treatments for elderly patients, and discussion of mechanisms of action for drugs used in sleep disorders, especially narcolepsy.
Pharmacotherapy of child and adolescent psychiatric disorders
2012,2011
This book fulfils an urgent need for an updated text on pediatric psychopharmacology. It takes a unique approach in discussing recent findings within the context of current issues, including economic and political ones. The book covers the emerging question of treating children who do not yet meet diagnostic criteria for psychosis, e.g, schizophrenia or bipolar disorder, but who are deemed to be at high risk. This is an active area of debate: such children are being treated in certain centers, while others reject this completely. The book addresses the antidepressant controversy, the placebo response and unique strategies for delineating this, and ways to optimize the differential between active medication and placebo. It reviews the impact of recent American Heart Association guidelines for monitoring children on stimulants and other psychotropics. It adheres closely to DSM-IV diagnostic criteria throughout. The book describes the use of newly approved drugs such as Lexapro for treating adolescent depression and the novel compound Intuniv. It covers the TADS and CAMS studies, which evaluated the use of SSRIs alone and in combination with cognitive behavioral therapy for adolescent depression. Other topics include treatment of bipolar disorders, the increasing popularity of generic equivalents, combination pharmacotherapy and the potential dangers of psychotropic medications.
* Third edition of the first ever book published on pediatric psychopharmacology from renowned editors.
* Incorporates current developments with regard to SSRIs, their indications and their safety issues, including possible associated suicidal behavior.
* Addresses concerns about cardiovascular side effects of the new stimulant medications available, and compares to other FDA-approved medications for ADHD.
* Features many tables, figures and pictorials, making it highly accessible and reader friendly.
Psychotropics and the Microbiome: a Chamber of Secrets
by
Clarke, Gerard
,
Cryan, John F
,
Dinan, Timothy G
in
Analgesics
,
Anticonvulsants
,
Antidepressants
2019
The human gut contains trillions of symbiotic bacteria that play a key role in programming different aspects of host physiology in health and disease. Psychotropic medications act on the central nervous system (CNS) and are used in the treatment of various psychiatric disorders. There is increasing emphasis on the bidirectional interaction between drugs and the gut microbiome. An expanding body of evidence supports the notion that microbes can metabolise drugs and vice versa drugs can modify the gut microbiota composition. In this review, we will first give a comprehensive introduction about this bidirectional interaction, then we will take into consideration different classes of psychotropics including antipsychotics, antidepressants, antianxiety drugs, anticonvulsants/mood stabilisers, opioid analgesics, drugs of abuse, alcohol, nicotine and xanthines. The varying effects of these widely used medications on microorganisms are becoming apparent from in vivo and in vitro studies. This has important implications for the future of psychopharmacology pipelines that will routinely need to consider the host microbiome during drug discovery and development.
Journal Article
Pharmacological treatment of mental disorders in primary health care
by
World Health Organization
in
administration and dosage
,
Clinical Competence
,
Developing Countries
2009
This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalised anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.
Efficacy of psychotropic drugs in functional dyspepsia: systematic review and meta-analysis
by
Moayyedi, Paul
,
Ford, Alexander C
,
Luthra, Pavit
in
Antidepressants
,
Antidepressive Agents, Tricyclic - therapeutic use
,
Antipsychotic Agents - therapeutic use
2017
ObjectiveFunctional dyspepsia (FD) is a chronic gastroduodenal disorder. Individuals with FD demonstrate visceral hypersensitivity, abnormal central pain processing, and low mood, but it is unclear whether psychotropic drugs are an effective treatment for the condition. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs).DesignMEDLINE, EMBASE, EMBASE Classic, PsychINFO and the Cochrane Controlled Trials Register were searched (up to June 2015) for RCTs recruiting adults with FD comparing psychotropic drugs with placebo. We contacted authors directly to maximise trial eligibility and minimise risk of bias for studies. Dichotomous symptom data were pooled to obtain relative risk (RR) of remaining symptomatic after therapy, with 95% CIs.ResultsThe search identified 2795 citations; 13 RCTs (1241 patients) were eligible. Ten trials were at low risk of bias. The RR of FD symptoms not improving with psychotropic drugs versus placebo was 0.78 (95% CI 0.68 to 0.91) (number needed to treat=6; 95% CI 4 to 16). However, benefit was limited to antipsychotics and tricyclic antidepressants. When only studies that excluded individuals with coexistent mood disorder were considered, there was no benefit. Total numbers of adverse events and adverse events leading to withdrawal were significantly more common, with a number needed to harm of 21 for both.ConclusionsPsychotropic drugs may be an effective treatment for FD, but the effect appears to be limited to antipsychotics and tricyclic antidepressants with fewer trials for other agents, meaning that firm conclusions for efficacy cannot be made. More data from high quality RCTs are required to support their use in the treatment of FD.
Journal Article