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Novel Prion Strain as Cause of Chronic Wasting Disease in a Moose, Finland
Our previous studies using gene-targeted mouse models of chronic wasting disease (CWD) demonstrated that Norway and North America cervids are infected with distinct prion strains that respond differently to naturally occurring amino acid variation at residue 226 of the prion protein. Here we performed transmissions in gene-targeted mice to investigate the properties of prions causing newly emergent CWD in moose in Finland. Although CWD prions from Finland and Norway moose had comparable responses to primary structural differences at residue 226, other distinctive criteria, including transmission kinetics, patterns of neuronal degeneration, and conformational features of prions generated in the brains of diseased mice, demonstrated that the strain properties of Finland moose CWD prions are different from those previously characterized in Norway CWD. Our findings add to a growing body of evidence for a diverse portfolio of emergent strains in Nordic countries that are etiologically distinct from the comparatively consistent strain profile of North America CWD.
Journal Article
Massive moose
\"Moose are the largest members of the deer family -- and they are large! The most massive moose are 7 feet (2 m) tall at the shoulder and weigh 1,300 pounds (600 kg). These herbivores aren't always gentle. They can use their colossal bodies to defend themselves from black bears, wolves, and other carnivores. Even hunters fear moose because angry moose sometimes can't be stopped by guns! This informative book, including a graphic organizer and essential science vocabulary, is a fresh look at the magnificent mammal called the moose.\"--Publisher's website.
Book
2 moose removed from Calgary suburb after kicking dog in backyard
According to iNaturalist, a citizen science website where people can track sightings and observations of wildlife worldwide, there have been more than 300 reported observations of moose in Calgary and the immediate area since 2020. The Miistakis Institute’s Calgary Connect wildlife monitoring program's remote cameras detected 242 moose in the city from 2017 to 2022, representing a small fraction of the 31,040 total detections of deer species. According to the program's latest report, moose \"have the most overlap with human activity\" of any wildlife species in Calgary, which according to Jordan-McLachlan means moose don't go out of their way to avoid areas frequented by people.
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