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A narrative review of inherited arrhythmogenic syndromes in young population: role of genetic diagnosis in exercise recommendations
by
Chipa, Fredy
, Balderrábano, Norma
, Martínez-Barrios, Estefanía
, Cerralbo, Patricia
, Diez-López, Carles
, Grazioli, Gonzalo
, Sarquella-Brugada, Georgia
, Greco, Andrea
, Díez-Escuté, Nuria
, Cesar, Sergi
, Cruzalegui, José
, Arbelo, Elena
, Campuzano, Oscar
, Toro, Rocío
in
Autopsies
/ Cardiac arrhythmia
/ Cardiology
/ Cardiomyopathy
/ Cardiovascular disease
/ Child
/ Disease prevention
/ Exercise
/ Genetics
/ Heart
/ Medical diagnosis
/ Pathology
/ Physical fitness
/ Review
/ Society
/ Young
2024
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A narrative review of inherited arrhythmogenic syndromes in young population: role of genetic diagnosis in exercise recommendations
by
Chipa, Fredy
, Balderrábano, Norma
, Martínez-Barrios, Estefanía
, Cerralbo, Patricia
, Diez-López, Carles
, Grazioli, Gonzalo
, Sarquella-Brugada, Georgia
, Greco, Andrea
, Díez-Escuté, Nuria
, Cesar, Sergi
, Cruzalegui, José
, Arbelo, Elena
, Campuzano, Oscar
, Toro, Rocío
in
Autopsies
/ Cardiac arrhythmia
/ Cardiology
/ Cardiomyopathy
/ Cardiovascular disease
/ Child
/ Disease prevention
/ Exercise
/ Genetics
/ Heart
/ Medical diagnosis
/ Pathology
/ Physical fitness
/ Review
/ Society
/ Young
2024
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Do you wish to request the book?
A narrative review of inherited arrhythmogenic syndromes in young population: role of genetic diagnosis in exercise recommendations
by
Chipa, Fredy
, Balderrábano, Norma
, Martínez-Barrios, Estefanía
, Cerralbo, Patricia
, Diez-López, Carles
, Grazioli, Gonzalo
, Sarquella-Brugada, Georgia
, Greco, Andrea
, Díez-Escuté, Nuria
, Cesar, Sergi
, Cruzalegui, José
, Arbelo, Elena
, Campuzano, Oscar
, Toro, Rocío
in
Autopsies
/ Cardiac arrhythmia
/ Cardiology
/ Cardiomyopathy
/ Cardiovascular disease
/ Child
/ Disease prevention
/ Exercise
/ Genetics
/ Heart
/ Medical diagnosis
/ Pathology
/ Physical fitness
/ Review
/ Society
/ Young
2024
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A narrative review of inherited arrhythmogenic syndromes in young population: role of genetic diagnosis in exercise recommendations
Journal Article
A narrative review of inherited arrhythmogenic syndromes in young population: role of genetic diagnosis in exercise recommendations
2024
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Overview
Sudden cardiac death is a rare but socially devastating event, especially if occurs in young people. Usually, this unexpected lethal event occurs during or just after exercise. One of the leading causes of sudden cardiac death is inherited arrhythmogenic syndromes, a group of genetic entities characterised by incomplete penetrance and variable expressivity. Exercise can be the trigger for malignant arrhythmias and even syncope in population with a genetic predisposition, being sudden cardiac death as the first symptom. Due to genetic origin, family members must be clinically assessed and genetically analysed after diagnosis or suspected diagnosis of a cardiac channelopathy. Early identification and adoption of personalised preventive measures is crucial to reduce risk of arrhythmias and avoid new lethal episodes. Despite exercise being recommended by the global population due to its beneficial effects on health, particular recommendations for these patients should be adopted considering the sport practised, level of demand, age, gender, arrhythmogenic syndrome diagnosed but also genetic diagnosis. Our review focuses on the role of genetic background in sudden cardiac death during exercise in child and young population.
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