Journal Article

Pancreatic cancer incidence and mortality trends: a population-based study

Fernandes, Fábia Cheyenne Gomes de Morais, Souza, Dyego Leandro Bezerra de, Souza, Ana Mayara Gomes de, Aiquoc, Kezauyn Miranda, Barbosa, Isabelle Ribeiro, Santos, Wesley dos

2022

Overview

Objectives To analyze trends in pancreatic cancer incidence and mortality in Latin American countries. Methods An ecological study with incidence data from the International Agency for Research on Cancer and mortality data from the World Health Organization. The trend of incidence by Joinpoint regression, the variation of the annual average and the 95% confidence interval were analyzed. Results There were increasing trends in incidence in Brazil, in males, aged 40-59 years, and reduction in Costa Rica. In females, there was stability in all age groups. The mortality rates increased in the elderly in Brazil (AAPC: 1.09%; 95% CI: 0.76; 1.42), Peru (AAPC: 1.76%; 95% CI: 0.36; 3.17) and El Salvador (AAPC: 2.88%; 95% CI: 0.38; 5.43), while in Mexico, there was a reduction. In females, this rate increased in Brazil (AAPC: 1.38%; 95% CI: 1.07; 1.69), Peru (AAPC: 2.25%; 95% CI: 0.68; 3.85), Chile (AAPC: 3.62%; 95% CI:1.96; 5.31), Nicaragua (AAPC: 2.51%; 95% CI: 0.36; 4.71) and Paraguay (AAPC: 1.17%; 95% CI: 0.37; 1.98) and a downward trend was observed in Colombia and Ecuador. Conclusions Pancreatic cancer had a higher incidence in the elderly population of both sexes and an increase of the mortality trend in females was noted.

• Publisher: Universidad Nacional de Colombia,Instituto de Salud Publica, Facultad de Medicina - Universidad Nacional de Colombia
• Subject: Cancer / Confidence intervals / Ecological studies / Females / Mortality / Older people / Pancreatic cancer / Population studies / Population-based studies / PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH / Reduction / Statistical analysis / Trends