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Measurable Residual Disease–Guided Therapy in Newly Diagnosed Myeloma

by Moreau, Philippe , Karlin, Lionel , Mary, Jean-Yves , Garderet, Laurent , Escoffre-Barbe, Martine , Gounot, Romain , De Prijck, Bernard , Braun, Thorsten , Chaleteix, Carine , Macro, Margaret , Rey, Philippe , Gay, Julie , Lambert, Jérôme , Pieragostini, Andrea , Mariette, Clara , Schiano, Jean-Marc , Avet-Loiseau, Hervé , Perrot, Aurore , Leleu, Xavier , Hulin, Cyrille , Corre, Jill , Manier, Salomon , Chalopin, Thomas , Touzeau, Cyrille , Mohty, Mohamad , Arnulf, Bertrand

in Adult / Aged / Antibodies, Monoclonal, Humanized - administration & dosage / Antineoplastic Combined Chemotherapy Protocols - administration & dosage / Bone Marrow Transplantation / Cancer / Consolidation Chemotherapy / Dexamethasone / Dexamethasone - administration & dosage / Female / Hematology / Hematopoietic Stem Cell Transplantation / Humans / Induction Chemotherapy - methods / Induction therapy / Lenalidomide - administration & dosage / Leukemia / Lymphoma / Male / Middle Aged / Multiple myeloma / Multiple Myeloma - diagnosis / Multiple Myeloma - mortality / Multiple Myeloma - therapy / Neoplasm, Residual / Next-generation sequencing / Oligopeptides - administration & dosage / Oncology / Stem cell transplantation / Transplantation, Autologous / Treatment Outcome / Treatments in Oncology

2025

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Measurable Residual Disease–Guided Therapy in Newly Diagnosed Myeloma

2025

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Measurable Residual Disease–Guided Therapy in Newly Diagnosed Myeloma

2025

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Journal Article

Measurable Residual Disease–Guided Therapy in Newly Diagnosed Myeloma

Moreau, Philippe,

Karlin, Lionel,

Mary, Jean-Yves,

Garderet, Laurent,

Escoffre-Barbe, Martine,

Gounot, Romain,

De Prijck, Bernard,

Braun, Thorsten,

Chaleteix, Carine,

Macro, Margaret,

Rey, Philippe,

Gay, Julie,

Lambert, Jérôme,

Pieragostini, Andrea,

Mariette, Clara,

Schiano, Jean-Marc,

Avet-Loiseau, Hervé,

Perrot, Aurore,

Leleu, Xavier,

Hulin, Cyrille,

Corre, Jill,

Manier, Salomon,

Chalopin, Thomas,

Touzeau, Cyrille,

Mohty, Mohamad,

Arnulf, Bertrand

2025

Overview

In newly diagnosed myeloma, ASCT showed no benefit over chemotherapy in patients without postinduction measurable residual disease, and tandem ASCT was not more effective than single ASCT in those with postinduction MRD.

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Publisher

Massachusetts Medical Society

Subject

Adult

/ Aged

/ Antibodies, Monoclonal, Humanized - administration & dosage

/ Antineoplastic Combined Chemotherapy Protocols - administration & dosage

/ Bone Marrow Transplantation

/ Cancer

/ Consolidation Chemotherapy