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When the Cause Is Not Crystal Clear
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When the Cause Is Not Crystal Clear
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When the Cause Is Not Crystal Clear
When the Cause Is Not Crystal Clear
Journal Article

When the Cause Is Not Crystal Clear

2020
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Overview
To the Editor: Forryan et al. (Jan. 2 issue) 1 discuss a woman with chronic kidney disease who had acute kidney injury from oxalate nephropathy caused by orlistat, a gastrointestinal lipase inhibitor. In the differential diagnosis, Forryan does not mention ethylene glycol poisoning, which is probably the most common cause of acute oxalate nephropathy. 2 The patient was not asked about toxic ingestions, a key omission, and the reader was not provided with measures of acid–base balance, which are integral to the management of renal failure and which usually reveal metabolic acidosis in cases of ethylene glycol intoxication. 3 In acute kidney injury, . . .