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Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes

by Kirkman, M Sue , Larkin, Mary E , Phillips, Lawrence S , Steffes, Michael , Lachin, John M , Tripputi, Mark , Younes, Naji , Krause-Steinrauf, Heidi , Kahn, Steven E , Bebu, Ionut , Green, Jennifer B , Wexler, Deborah J , Nathan, David M , Tiktin, Margaret , Pop-Busui, Rodica , Cherrington, Andrea L , Buse, John B , Burch, Henry B , Fortmann, Stephen P

in Albuminuria - etiology / Albuminuria - prevention & control / Antidiabetics / Blood glucose / Blood Glucose - analysis / Blood pressure / Cardiology / Cardiology General / Cardiovascular disease / Cardiovascular diseases / Cardiovascular Diseases - etiology / Cardiovascular Diseases - prevention & control / Chronic Kidney Disease / Clinical Medicine / Clinical trials / Comparative Effectiveness Research / Congestive heart failure / Creatinine / Death / Diabetes / Diabetes Complications - etiology / Diabetes Complications - prevention & control / Diabetes mellitus (non-insulin dependent) / Diabetes Mellitus, Type 2 - complications / Diabetes Mellitus, Type 2 - drug therapy / Diabetic Neuropathies - diagnosis / Diabetic Neuropathies - etiology / Diabetic Neuropathies - prevention & control / Drug Therapy, Combination / Dyslipidemia / Dyslipidemias - etiology / Dyslipidemias - prevention & control / Endocrinology / FDA approval / Glomerular Filtration Rate / Glucose / Glycated Hemoglobin - analysis / Heart Failure - etiology / Heart Failure - prevention & control / Hemoglobin / Humans / Hypertension / Hypertension - etiology / Hypertension - prevention & control / Hypoglycemia / Hypoglycemic Agents - adverse effects / Hypoglycemic Agents - therapeutic use / Insulin / Insulin Glargine - adverse effects / Insulin Glargine - therapeutic use / Kidney diseases / Liraglutide - adverse effects / Liraglutide - therapeutic use / Metabolism / Metformin / Metformin - adverse effects / Metformin - therapeutic use / Microvasculature / Microvessels - drug effects / Nephrology / Outpatient-Based Clinical Medicine / Peripheral neuropathy / Risk factors / Sitagliptin Phosphate - adverse effects / Sitagliptin Phosphate - therapeutic use / Sulfonylurea Compounds - adverse effects / Sulfonylurea Compounds - therapeutic use

2022

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Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes

2022

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2022

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Journal Article

Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes

Kirkman, M Sue,

Larkin, Mary E,

Phillips, Lawrence S,

Steffes, Michael,

Lachin, John M,

Tripputi, Mark,

Younes, Naji,

Krause-Steinrauf, Heidi,

Kahn, Steven E,

Bebu, Ionut,

Green, Jennifer B,

Wexler, Deborah J,

Nathan, David M,

Tiktin, Margaret,

Pop-Busui, Rodica,

Cherrington, Andrea L,

Buse, John B,

Burch, Henry B,

Fortmann, Stephen P

2022

Overview

In a secondary analysis comparing the effect of insulin glargine, glimepiride, liraglutide, and sitagliptin, added to metformin, on the incidences of microvascular complications and death, no material between-group differences were seen.

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Publisher

Massachusetts Medical Society

Subject

Albuminuria - etiology

/ Albuminuria - prevention & control

/ Antidiabetics

/ Blood glucose

/ Blood Glucose - analysis

/ Blood pressure

/ Cardiology