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Tranexamic Acid for the Prevention of Blood Loss after Vaginal Delivery

by Perrotin, Franck , Doret-Dion, Muriel , Sentilhes, Loïc , Daniel, Valérie , Kayem, Gilles , Huissoud, Cyril , Darsonval, Astrid , Desbrière, Raoul , Deneux-Tharaux, Catherine , Bohec, Caroline , Azria, Elie , Sénat, Marie-Victoire , Seco, Aurélien , Fuchs, Florent , Ducarme, Guillaume , Chrétien, Jean-Marie , Winer, Norbert , Vardon, Delphine , Deruelle, Philippe , Le Ray, Camille

in Acids / Adult / Antifibrinolytic agents / Antifibrinolytic Agents - adverse effects / Antifibrinolytic Agents - therapeutic use / Childbirth & labor / Double-Blind Method / Drug Therapy, Combination / Female / Fetuses / Gestation / Hemorrhage / Human health and pathology / Humans / Injections, Intravenous / Intention to Treat Analysis / Life Sciences / Oxytocics - therapeutic use / Oxytocin / Oxytocin - therapeutic use / Postpartum / Postpartum Hemorrhage - prevention & control / Pregnancy / Prevention / Risk Factors / Thromboembolism / Thromboembolism - chemically induced / Tranexamic Acid - adverse effects / Tranexamic Acid - therapeutic use / Vagina / Womens health

2018

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Tranexamic Acid for the Prevention of Blood Loss after Vaginal Delivery

2018

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2018

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Journal Article

Tranexamic Acid for the Prevention of Blood Loss after Vaginal Delivery

Perrotin, Franck,

Doret-Dion, Muriel,

Sentilhes, Loïc,

Daniel, Valérie,

Kayem, Gilles,

Huissoud, Cyril,

Darsonval, Astrid,

Desbrière, Raoul,

Deneux-Tharaux, Catherine,

Bohec, Caroline,

Azria, Elie,

Sénat, Marie-Victoire,

Seco, Aurélien,

Fuchs, Florent,

Ducarme, Guillaume,

Chrétien, Jean-Marie,

Winer, Norbert,

Vardon, Delphine,

Deruelle, Philippe,

Le Ray, Camille

2018

Overview

In a multicenter, double-blind, randomized, controlled trial involving women with vaginal delivery who received prophylactic oxytocin, tranexamic acid after delivery did not lead to a significantly lower rate of postpartum hemorrhage than placebo.

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Publisher

Massachusetts Medical Society

Subject

Acids

/ Adult

/ Antifibrinolytic agents

/ Antifibrinolytic Agents - adverse effects

/ Antifibrinolytic Agents - therapeutic use

/ Childbirth & labor

/ Double-Blind Method