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Empagliflozin in Heart Failure with a Preserved Ejection Fraction

by Piña, Ileana L , Gonzalez-Juanatey, Jose R , Zhang, Jian , Marx, Nikolaus , Anker, Stefan D , Zannad, Faiez , Perrone, Sergio V , Gomez-Mesa, Juan Esteban , Filippatos, Gerasimos , Brueckmann, Martina , Janssens, Stefan , Taddei, Stefano , Giannetti, Nadia , Chuquiure-Valenzuela, Eduardo , Sim, David , Squire, Iain , Zeller, Cordula , Böhm, Michael , Butler, Javed , Januzzi, James L , Senni, Michele , Chopra, Vijay , Jamal, Waheed , Bocchi, Edimar , Tsutsui, Hiroyuki , Lam, Carolyn Su Ping , Brunner–La Rocca, Hans-Peter , Vinereanu, Dragos , Sattar, Naveed , Spinar, Jindrich , Schnee, Janet M , Pocock, Stuart J , Ponikowski, Piotr , Packer, Milton , Choi, Dong-Ju , Ferreira, João P , Nicholls, Stephen J , Carson, Peter , Merkely, Bela , Verma, Subodh , Schnaidt, Sven

in Adult / Antidiabetics / Benzhydryl Compounds - administration & dosage / Benzhydryl Compounds - adverse effects / Cardiology / Cardiology and cardiovascular system / Cardiology General / Cardiovascular diseases / Cardiovascular Diseases - mortality / Cardiovascular Diseases - prevention & control / Chronic Disease / Congestive heart failure / Diabetes / Diabetes mellitus / Double-Blind Method / Ejection fraction / Female / Glucosides - administration & dosage / Glucosides - adverse effects / Heart Failure / Heart Failure - drug therapy / Heart Failure - physiopathology / Hospitalization - statistics & numerical data / Human health and pathology / Humans / Hypotension / Life Sciences / Male / Patient safety / Placebos / Sodium-glucose cotransporter / Sodium-Glucose Transporter 2 Inhibitors - administration & dosage / Sodium-Glucose Transporter 2 Inhibitors - adverse effects / Statistical analysis / Stroke Volume / Urinary tract

2021

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Empagliflozin in Heart Failure with a Preserved Ejection Fraction

2021

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Empagliflozin in Heart Failure with a Preserved Ejection Fraction

2021

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Journal Article

Empagliflozin in Heart Failure with a Preserved Ejection Fraction

Piña, Ileana L,

Gonzalez-Juanatey, Jose R,

Zhang, Jian,

Marx, Nikolaus,

Anker, Stefan D,

Zannad, Faiez,

Perrone, Sergio V,

Gomez-Mesa, Juan Esteban,

Filippatos, Gerasimos,

Brueckmann, Martina,

Janssens, Stefan,

Taddei, Stefano,

Giannetti, Nadia,

Chuquiure-Valenzuela, Eduardo,

Sim, David,

Squire, Iain,

Zeller, Cordula,

Böhm, Michael,

Butler, Javed,

Januzzi, James L,

Senni, Michele,

Chopra, Vijay,

Jamal, Waheed,

Bocchi, Edimar,

Tsutsui, Hiroyuki,

Lam, Carolyn Su Ping,

Brunner–La Rocca, Hans-Peter,

Vinereanu, Dragos,

Sattar, Naveed,

Spinar, Jindrich,

Schnee, Janet M,

Pocock, Stuart J,

Ponikowski, Piotr,

Packer, Milton,

Choi, Dong-Ju,

Ferreira, João P,

Nicholls, Stephen J,

Carson, Peter,

Merkely, Bela,

Verma, Subodh,

Schnaidt, Sven

2021

Overview

In a randomized trial, 5988 patients with heart failure with preserved ejection fraction were assigned to receive either empagliflozin or placebo in addition to usual therapy. At a median of 26 months, the empagliflozin group had a lower incidence of cardiovascular death or hospitalization for heart failure than the placebo group.

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Publisher

Massachusetts Medical Society

Subject

Adult

/ Antidiabetics

/ Benzhydryl Compounds - administration & dosage

/ Benzhydryl Compounds - adverse effects

/ Cardiology

/ Cardiology and cardiovascular system

/ Cardiology General