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Soft-Tissue Sarcoma in Adults: An Update on the Current State of Histiotype-Specific Management in an Era of Personalized Medicine
by
Cardona, Kenneth
, Gronchi, Alessandro
, Gamboa, Adriana C
in
Clinical trials
/ Precision medicine
/ Retroperitoneum
/ Sarcoma
/ Surgery
/ Tumors
2020
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Soft-Tissue Sarcoma in Adults: An Update on the Current State of Histiotype-Specific Management in an Era of Personalized Medicine
by
Cardona, Kenneth
, Gronchi, Alessandro
, Gamboa, Adriana C
in
Clinical trials
/ Precision medicine
/ Retroperitoneum
/ Sarcoma
/ Surgery
/ Tumors
2020
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Soft-Tissue Sarcoma in Adults: An Update on the Current State of Histiotype-Specific Management in an Era of Personalized Medicine
Journal Article
Soft-Tissue Sarcoma in Adults: An Update on the Current State of Histiotype-Specific Management in an Era of Personalized Medicine
2020
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Overview
Soft-tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies, with over 100 different histologic subtypes occurring predominately in the trunk, extremity, and retroperitoneum. This low incidence is further complicated by their variable presentation, behavior, and long-term outcomes, which emphasize the importance of centralized care in specialized centers with a multidisciplinary team approach. In the last decade, there has been an effort to improve the quality of care for patients with STS based on anatomic site and histology, and multiple ongo-ing clinical trials are focusing on tailoring therapy to histologic subtype. This report summarizes the latest evidence guiding the histiotype-specific management of ex-tremity/truncal and retroperitoneal STS with regard to surgery, radiation, and chem-otherapy.
Publisher
Wiley Subscription Services, Inc
Subject
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