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Herpesvirus: an underestimated virus

by Rechenchoski, Daniele Zendrini , Faccin-Galhardi, Ligia Carla , Nozawa, Carlos , Linhares, Rosa Elisa Carvalho

in Antiviral Agents - therapeutic use / Antiviral drugs / Applied Microbiology / Biomedical and Life Sciences / Cytomegalovirus / Disease / disease control / Drug resistance / drug toxicity / Environmental Engineering/Biotechnology / Epidemiology / Genes / Genomes / Glycoproteins / Health services / Heparan sulfate / Herpes Genitalis - diagnosis / Herpes Genitalis - drug therapy / Herpes Genitalis - epidemiology / Herpes Genitalis - immunology / Herpes simplex / Herpes Simplex - diagnosis / Herpes Simplex - drug therapy / Herpes Simplex - epidemiology / Herpes Simplex - immunology / Herpes viruses / Herpesviridae / Herpesvirus 1, Human - classification / Herpesvirus 1, Human - drug effects / Herpesvirus 1, Human - growth & development / Herpesvirus 1, Human - pathogenicity / Herpesvirus 2, Human - classification / Herpesvirus 2, Human - drug effects / Herpesvirus 2, Human - growth & development / Herpesvirus 2, Human - pathogenicity / Humans / Immunocompromised Host / Immunology / Infant, Newborn / Infections / Life Sciences / Microbiology / Mortality / Neonates / Palliative care / Pathogenesis / patients / prognosis / Prophylaxis / Proteins / RNA polymerase / Taxonomy / therapeutics / Toxicity / Vaccines / Virus Replication - drug effects / Virus Replication - genetics / Viruses

2017

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Herpesvirus: an underestimated virus

by Rechenchoski, Daniele Zendrini , Faccin-Galhardi, Ligia Carla , Nozawa, Carlos , Linhares, Rosa Elisa Carvalho

2017

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Herpesvirus: an underestimated virus

by Rechenchoski, Daniele Zendrini , Faccin-Galhardi, Ligia Carla , Nozawa, Carlos , Linhares, Rosa Elisa Carvalho

2017

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Journal Article

Herpesvirus: an underestimated virus

Rechenchoski, Daniele Zendrini,

Faccin-Galhardi, Ligia Carla,

Nozawa, Carlos,

Linhares, Rosa Elisa Carvalho

2017

Overview

Herpes simplex virus (HSV) infections are common and widespread; nevertheless, their outcome can be of unpredictable prognosis in neonates and in immunosuppressed patients. Anti-HSV therapy is effective, but the emergence of drug-resistant strains or the drug toxicity that hamper the treatment is of great concern. Vaccine has not yet shown relevant benefit; therefore, palliative prophylactic measures have been adopted to prevent diseases. This short review proposes to present concisely the history of HSV, its taxonomy, physical structure, and replication and to explore the pathogenesis of the infection, clinical manifestations, laboratory diagnosis, treatment, prophylaxis and epidemiology of the diseases.

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Publisher

Springer Netherlands,Springer Nature B.V

Subject

Antiviral Agents - therapeutic use

/ Antiviral drugs

/ Applied Microbiology

/ Biomedical and Life Sciences

/ Cytomegalovirus

/ Disease

/ disease control