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Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development

by Li, Quanzi , Khan, Muhammad Sarwar , Islam, Md. Monirul , Li, Jia , El-Sappah, Ahmed H. , Wang, Yu , Zhao, Xianming , Huang, Qiulan , Mir, Reyazul Rouf , Yan, Kuan , El-Tarabily, Khaled A. , Abbas, Manzar

in 5' Untranslated regions / Albinism / Biosynthesis / Cell fate / CRISPR / CRISPR/Cas9 / Crop production / DNA methylation / Epigenetics / Gene expression / Gene silencing / Genetic engineering / genomics imprinting / Methylation / MicroRNAs / Molecular modelling / Negative feedback / paramutation / Pathogens / Plant growth / Plant Science / Post-transcription / post-transcriptional gene silencing / Proteins / RNA polymerase / RNAi / transcriptional gene silencing

2021

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Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development

2021

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2021

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Journal Article

Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development

Li, Quanzi,

Khan, Muhammad Sarwar,

Islam, Md. Monirul,

Li, Jia,

El-Sappah, Ahmed H.,

Wang, Yu,

Zhao, Xianming,

Huang, Qiulan,

Mir, Reyazul Rouf,

Yan, Kuan,

El-Tarabily, Khaled A.,

Abbas, Manzar

2021

Overview

Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism. In plants, gene silencing occurs via transcriptional gene silencing (TGS) and post-transcriptional gene silencing (PTGS). TGS obscures transcription via the methylation of 5′ untranslated region (5′UTR), whereas PTGS causes the methylation of a coding region to result in transcript degradation. In this review, we summarized the history and molecular mechanisms of gene silencing and underlined its specific role in plant growth and crop production.

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Publisher

Frontiers Media SA,Frontiers Media S.A

Subject

5' Untranslated regions

/ CRISPR