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Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure
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Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure
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Journal Article
Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure
2015
Overview
Patients with heart failure and sleep apnea were assigned to adaptive servo-ventilation or control. The rate of death, lifesaving cardiovascular intervention, or hospitalization for heart failure did not differ significantly between groups, but mortality was higher with adaptive servo-ventilation.
Sleep-disordered breathing is common in patients who have heart failure with reduced ejection fraction, with reported prevalence rates of 50 to 75%.
1
Obstructive sleep apnea occurs more often in patients with heart failure than in the general population. Central sleep apnea, which may manifest as Cheyne–Stokes respiration, is found in 25 to 40% of patients who have heart failure with reduced ejection fraction.
2
The prevalence of central sleep apnea increases in parallel with increasing severity of heart failure
1
and worsening cardiac dysfunction.
3
There are a number of mechanisms by which central sleep apnea may be detrimental to cardiac function, including . . .
Publisher
Massachusetts Medical Society
Subject
/ Apnea
/ Cardiovascular Diseases - etiology
/ Cardiovascular Diseases - mortality
/ Death
/ Female
/ Heart Failure, Systolic - complications
/ Heart Failure, Systolic - physiopathology
/ Heart Failure, Systolic - therapy
/ Humans
/ Male
/ Patients
/ Positive-Pressure Respiration - adverse effects
/ Positive-Pressure Respiration - methods
/ Pressure
/ Sleep
/ Sleep Apnea, Central - complications
