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Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder

by Marler, Sarah , Luo, Sheng , Mullett, Jennifer E , She, Lilin , Shuffrey, Lauren C , Siper, Paige , McDougle, Christopher J , Chandrasekhar, Tara , Scheer, Abby , Veenstra-VanderWeele, Jeremy , Zappone, Brooke , Crosson, Hope , Kim, Soo-Jeong , Weissman, Jordana , Palumbo, Michelle L , Montgomery, Alicia , Giamberardino, Stephanie N , Hong, Natalie , Gregory, Simon G , Trelles, M.D. Pilar , Bhapkar, Manjushri , King, Bryan H , Rockhill, Carol M , Siecinski, Stephen K , Minjarez, Mendy , Kolevzon, Alexander , Johnson, Jacqueline L , Spanos, Marina , Alderman, Cheryl , Dean, Russell , Witters Cundiff, Allyson , Sanders, Kevin B , Sikich, Linmarie , Nowinski, Lisa A

in Administration, Intranasal / Adolescence / Adolescent / Adolescents / Adverse events / Autism / Autism Spectrum Disorder - drug therapy / Autism Spectrum Disorder - psychology / Behavior / Caregivers / Child / Child & adolescent mental health / Child, Preschool / Children / Clinical trials / Cognitive ability / Double-Blind Method / Female / Humans / Least-Squares Analysis / Male / Mental disorders / Neurology / Neurosurgery / Neurosurgery General / Oxytocin / Oxytocin - administration & dosage / Oxytocin - adverse effects / Oxytocin - therapeutic use / Pediatrics / Pediatrics General / Placebos / Psychiatry / Psychiatry General / Social Behavior / Social research / Social Skills / Teenagers / Treatment Failure

2021

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Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder

2021

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2021

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Journal Article

Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder

Marler, Sarah,

Luo, Sheng,

Mullett, Jennifer E,

She, Lilin,

Shuffrey, Lauren C,

Siper, Paige,

McDougle, Christopher J,

Chandrasekhar, Tara,

Scheer, Abby,

Veenstra-VanderWeele, Jeremy,

Zappone, Brooke,

Crosson, Hope,

Kim, Soo-Jeong,

Weissman, Jordana,

Palumbo, Michelle L,

Montgomery, Alicia,

Giamberardino, Stephanie N,

Hong, Natalie,

Gregory, Simon G,

Trelles, M.D. Pilar,

Bhapkar, Manjushri,

King, Bryan H,

Rockhill, Carol M,

Siecinski, Stephen K,

Minjarez, Mendy,

Kolevzon, Alexander,

Johnson, Jacqueline L,

Spanos, Marina,

Alderman, Cheryl,

Dean, Russell,

Witters Cundiff, Allyson,

Sanders, Kevin B,

Sikich, Linmarie,

Nowinski, Lisa A

2021

Overview

Intranasal oxytocin therapy has been used to improve various aspects of autism spectrum disorder on the basis of tenuous results from small studies. In a randomized trial involving 290 participants 3 to 17 years of age with autism spectrum disorder, daily use of oxytocin did not improve measures of social interaction as compared with placebo over a period of 24 weeks.

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Publisher

Massachusetts Medical Society

Subject

Administration, Intranasal

/ Autism

/ Autism Spectrum Disorder - drug therapy