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Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum
by
Davis, John S.
, Przygrodzka, Emilia
, Plewes, Michele R.
in
Adenosine
/ Angiogenesis
/ Animals
/ Artificial insemination
/ Autophagy
/ Cell cycle
/ Cholesterol
/ Corpus Luteum - cytology
/ Corpus Luteum - metabolism
/ Enzymes
/ Female
/ Hogs
/ Hormones
/ Humans
/ Kinases
/ Lipoproteins
/ Luteal Cells - cytology
/ Luteal Cells - ultrastructure
/ Luteinizing Hormone - metabolism
/ Metabolism
/ Mitochondria
/ Morphology
/ Organelles - metabolism
/ Ovaries
/ Ovulation
/ Phosphorylation
/ Pregnancy
/ Proteins
/ Review
/ Sheep
/ Signal Transduction
/ Steroids
2021
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Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum
by
Davis, John S.
, Przygrodzka, Emilia
, Plewes, Michele R.
in
Adenosine
/ Angiogenesis
/ Animals
/ Artificial insemination
/ Autophagy
/ Cell cycle
/ Cholesterol
/ Corpus Luteum - cytology
/ Corpus Luteum - metabolism
/ Enzymes
/ Female
/ Hogs
/ Hormones
/ Humans
/ Kinases
/ Lipoproteins
/ Luteal Cells - cytology
/ Luteal Cells - ultrastructure
/ Luteinizing Hormone - metabolism
/ Metabolism
/ Mitochondria
/ Morphology
/ Organelles - metabolism
/ Ovaries
/ Ovulation
/ Phosphorylation
/ Pregnancy
/ Proteins
/ Review
/ Sheep
/ Signal Transduction
/ Steroids
2021
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Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum
by
Davis, John S.
, Przygrodzka, Emilia
, Plewes, Michele R.
in
Adenosine
/ Angiogenesis
/ Animals
/ Artificial insemination
/ Autophagy
/ Cell cycle
/ Cholesterol
/ Corpus Luteum - cytology
/ Corpus Luteum - metabolism
/ Enzymes
/ Female
/ Hogs
/ Hormones
/ Humans
/ Kinases
/ Lipoproteins
/ Luteal Cells - cytology
/ Luteal Cells - ultrastructure
/ Luteinizing Hormone - metabolism
/ Metabolism
/ Mitochondria
/ Morphology
/ Organelles - metabolism
/ Ovaries
/ Ovulation
/ Phosphorylation
/ Pregnancy
/ Proteins
/ Review
/ Sheep
/ Signal Transduction
/ Steroids
2021
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Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum
Journal Article
Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum
2021
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Overview
The corpus luteum is an endocrine gland that synthesizes the steroid hormone progesterone. luteinizing hormone (LH) is a key luteotropic hormone that stimulates ovulation, luteal development, progesterone biosynthesis, and maintenance of the corpus luteum. Luteotropic and luteolytic factors precisely regulate luteal structure and function; yet, despite recent scientific progress within the past few years, the exact mechanisms remain largely unknown. In the present review, we summarize the recent progress towards understanding cellular changes induced by LH in steroidogenic luteal cells. Herein, we will focus on the effects of LH on inter-organelle communication and steroid biosynthesis, and how LH regulates key protein kinases (i.e., AMPK and MTOR) responsible for controlling steroidogenesis and autophagy in luteal cells.
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