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A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy

by McRobbie, Hayden J , Li, Jinshuo , Phillips-Waller, Anna , Hajek, Peter , Goniewicz, Maciej , Ross, Louise , Wu, Qi , Sasieni, Peter , Myers Smith, Katie , Dawkins, Lynne , Przulj, Dunja , Pesola, Francesca , Bisal, Natalie , Parrott, Steve

in Adult / Cancer / Carbon monoxide / Cigarettes / Clinical trials / Cough / Drug addiction / Electronic cigarettes / Electronic Nicotine Delivery Systems / Ethics / Evidence-based medicine / Female / Flavors / Health services / Humans / Irritation / Male / Medical research / Middle Aged / Nausea / Nicotine / Nicotine - administration & dosage / Pharynx / Smoking cessation / Smoking Cessation - methods / Tobacco Use Cessation Devices - adverse effects / Tobacco Use Disorder - therapy / Treatment Outcome / Vaping - adverse effects / Wheezing

2019

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A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy

2019

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2019

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Journal Article

A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy

McRobbie, Hayden J,

Li, Jinshuo,

Phillips-Waller, Anna,

Hajek, Peter,

Goniewicz, Maciej,

Ross, Louise,

Wu, Qi,

Sasieni, Peter,

Myers Smith, Katie,

Dawkins, Lynne,

Przulj, Dunja,

Pesola, Francesca,

Bisal, Natalie,

Parrott, Steve

2019

Overview

In a randomized trial involving 886 smokers, e-cigarettes were more effective than nicotine-replacement therapy with respect to the 1-year abstinence rate (18% vs. 10%). Throat or mouth irritation was more common in the e-cigarette group, and nausea was more common in the nicotine-replacement group.

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Publisher

Massachusetts Medical Society

Subject

/ Cancer

/ Cough