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Maintenance Fluconazole Therapy for Recurrent Vulvovaginal Candidiasis
by
Rompalo, Anne
, Wiesenfeld, Harold C
, Edwards, Libby
, Danna, Penny
, Sobel, Jack D
, Livengood, Charles
, Sperling, Malcolm
, Von Thron, James
, Martens, Mark
, Horowitz, Benson
, Panzer, Helene
, Chu, Teng-Chiao
, Hooton, Thomas M
in
Administration, Oral
/ Adult
/ Antifungal Agents - adverse effects
/ Antifungal Agents - therapeutic use
/ Biological and medical sciences
/ Candida albicans - isolation & purification
/ Candida glabrata - isolation & purification
/ Candidiasis, Vulvovaginal - drug therapy
/ Candidiasis, Vulvovaginal - prevention & control
/ Double-Blind Method
/ Drug Administration Schedule
/ Drug Resistance, Fungal
/ Female
/ Fluconazole - adverse effects
/ Fluconazole - therapeutic use
/ General aspects
/ HIV
/ Human immunodeficiency virus
/ Humans
/ Logistic Models
/ Medical research
/ Medical sciences
/ Remission Induction
/ Secondary Prevention
/ Time Factors
/ Vagina - microbiology
2004
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Maintenance Fluconazole Therapy for Recurrent Vulvovaginal Candidiasis
by
Rompalo, Anne
, Wiesenfeld, Harold C
, Edwards, Libby
, Danna, Penny
, Sobel, Jack D
, Livengood, Charles
, Sperling, Malcolm
, Von Thron, James
, Martens, Mark
, Horowitz, Benson
, Panzer, Helene
, Chu, Teng-Chiao
, Hooton, Thomas M
in
Administration, Oral
/ Adult
/ Antifungal Agents - adverse effects
/ Antifungal Agents - therapeutic use
/ Biological and medical sciences
/ Candida albicans - isolation & purification
/ Candida glabrata - isolation & purification
/ Candidiasis, Vulvovaginal - drug therapy
/ Candidiasis, Vulvovaginal - prevention & control
/ Double-Blind Method
/ Drug Administration Schedule
/ Drug Resistance, Fungal
/ Female
/ Fluconazole - adverse effects
/ Fluconazole - therapeutic use
/ General aspects
/ HIV
/ Human immunodeficiency virus
/ Humans
/ Logistic Models
/ Medical research
/ Medical sciences
/ Remission Induction
/ Secondary Prevention
/ Time Factors
/ Vagina - microbiology
2004
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Maintenance Fluconazole Therapy for Recurrent Vulvovaginal Candidiasis
by
Rompalo, Anne
, Wiesenfeld, Harold C
, Edwards, Libby
, Danna, Penny
, Sobel, Jack D
, Livengood, Charles
, Sperling, Malcolm
, Von Thron, James
, Martens, Mark
, Horowitz, Benson
, Panzer, Helene
, Chu, Teng-Chiao
, Hooton, Thomas M
in
Administration, Oral
/ Adult
/ Antifungal Agents - adverse effects
/ Antifungal Agents - therapeutic use
/ Biological and medical sciences
/ Candida albicans - isolation & purification
/ Candida glabrata - isolation & purification
/ Candidiasis, Vulvovaginal - drug therapy
/ Candidiasis, Vulvovaginal - prevention & control
/ Double-Blind Method
/ Drug Administration Schedule
/ Drug Resistance, Fungal
/ Female
/ Fluconazole - adverse effects
/ Fluconazole - therapeutic use
/ General aspects
/ HIV
/ Human immunodeficiency virus
/ Humans
/ Logistic Models
/ Medical research
/ Medical sciences
/ Remission Induction
/ Secondary Prevention
/ Time Factors
/ Vagina - microbiology
2004
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Maintenance Fluconazole Therapy for Recurrent Vulvovaginal Candidiasis
Journal Article
Maintenance Fluconazole Therapy for Recurrent Vulvovaginal Candidiasis
2004
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Overview
This double-blind trial involving 387 women with recurrent candidiasis evaluated the effectiveness of a regimen of 150 mg of oral fluconazole once per week. Six months after the completion of therapy, 90.8 percent of the women in the fluconazole group remained free of candidiasis, as compared with 35.9 percent in the placebo group.
This double-blind trial evaluated the effectiveness of a regimen of oral fluconazole once per week.
Since recurrent vulvovaginal candidiasis is estimated to occur in 5 to 8 percent of women during their reproductive years, millions of women worldwide are affected by the condition.
1
–
3
Not considered a typical sexually transmitted infection, recurrent vulvovaginal candidiasis affects immunocompetent, healthy women in all strata of society.
2
,
4
Although the condition has several causes, the majority of women with recurrent infection have no recognizable risk factors.
5
,
6
Frequent recurrences of symptomatic vulvovaginitis result in considerable suffering and cost and have a markedly negative effect on sexual relations.
7
Management approaches include treatment of each individual episode or use of prophylactic . . .
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Antifungal Agents - adverse effects
/ Antifungal Agents - therapeutic use
/ Biological and medical sciences
/ Candida albicans - isolation & purification
/ Candida glabrata - isolation & purification
/ Candidiasis, Vulvovaginal - drug therapy
/ Candidiasis, Vulvovaginal - prevention & control
/ Drug Administration Schedule
/ Female
/ Fluconazole - adverse effects
/ Fluconazole - therapeutic use
/ HIV
/ Human immunodeficiency virus
/ Humans
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