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Elsholtzia ciliata (Thunb.) Hyl. Extracts from Different Plant Parts: Phenolic Composition, Antioxidant, and Anti-Inflammatory Activities
by
Bernatoniene, Jurga
, Pudziuvelyte, Lauryna
, Sadauskiene, Ilona
, Liaudanskas, Mindaugas
, Jekabsone, Aiste
in
Animals
/ anti-inflammatory activity
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - isolation & purification
/ Anti-Inflammatory Agents - pharmacology
/ antioxidant
/ Antioxidants - chemistry
/ Antioxidants - isolation & purification
/ Antioxidants - pharmacology
/ Cell Survival - drug effects
/ Chromatography, High Pressure Liquid
/ elsholtzia ciliata
/ Herbal medicine
/ Herbs
/ hplc–abts post-column
/ Inflammation Mediators - metabolism
/ Lamiaceae - chemistry
/ Macrophages, Peritoneal - drug effects
/ Macrophages, Peritoneal - metabolism
/ Mice
/ natural compounds
/ Oxidation
/ Phenols - chemistry
/ Phenols - isolation & purification
/ Phenols - pharmacology
/ Phytochemicals - chemistry
/ Phytochemicals - isolation & purification
/ Phytochemicals - pharmacology
/ Plant Components, Aerial - chemistry
/ Plant Extracts - chemistry
/ Plant Extracts - isolation & purification
/ Plant Extracts - pharmacology
/ Polyphenols
/ rosmarinic acid
/ Studies
2020
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Elsholtzia ciliata (Thunb.) Hyl. Extracts from Different Plant Parts: Phenolic Composition, Antioxidant, and Anti-Inflammatory Activities
by
Bernatoniene, Jurga
, Pudziuvelyte, Lauryna
, Sadauskiene, Ilona
, Liaudanskas, Mindaugas
, Jekabsone, Aiste
in
Animals
/ anti-inflammatory activity
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - isolation & purification
/ Anti-Inflammatory Agents - pharmacology
/ antioxidant
/ Antioxidants - chemistry
/ Antioxidants - isolation & purification
/ Antioxidants - pharmacology
/ Cell Survival - drug effects
/ Chromatography, High Pressure Liquid
/ elsholtzia ciliata
/ Herbal medicine
/ Herbs
/ hplc–abts post-column
/ Inflammation Mediators - metabolism
/ Lamiaceae - chemistry
/ Macrophages, Peritoneal - drug effects
/ Macrophages, Peritoneal - metabolism
/ Mice
/ natural compounds
/ Oxidation
/ Phenols - chemistry
/ Phenols - isolation & purification
/ Phenols - pharmacology
/ Phytochemicals - chemistry
/ Phytochemicals - isolation & purification
/ Phytochemicals - pharmacology
/ Plant Components, Aerial - chemistry
/ Plant Extracts - chemistry
/ Plant Extracts - isolation & purification
/ Plant Extracts - pharmacology
/ Polyphenols
/ rosmarinic acid
/ Studies
2020
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Elsholtzia ciliata (Thunb.) Hyl. Extracts from Different Plant Parts: Phenolic Composition, Antioxidant, and Anti-Inflammatory Activities
by
Bernatoniene, Jurga
, Pudziuvelyte, Lauryna
, Sadauskiene, Ilona
, Liaudanskas, Mindaugas
, Jekabsone, Aiste
in
Animals
/ anti-inflammatory activity
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - isolation & purification
/ Anti-Inflammatory Agents - pharmacology
/ antioxidant
/ Antioxidants - chemistry
/ Antioxidants - isolation & purification
/ Antioxidants - pharmacology
/ Cell Survival - drug effects
/ Chromatography, High Pressure Liquid
/ elsholtzia ciliata
/ Herbal medicine
/ Herbs
/ hplc–abts post-column
/ Inflammation Mediators - metabolism
/ Lamiaceae - chemistry
/ Macrophages, Peritoneal - drug effects
/ Macrophages, Peritoneal - metabolism
/ Mice
/ natural compounds
/ Oxidation
/ Phenols - chemistry
/ Phenols - isolation & purification
/ Phenols - pharmacology
/ Phytochemicals - chemistry
/ Phytochemicals - isolation & purification
/ Phytochemicals - pharmacology
/ Plant Components, Aerial - chemistry
/ Plant Extracts - chemistry
/ Plant Extracts - isolation & purification
/ Plant Extracts - pharmacology
/ Polyphenols
/ rosmarinic acid
/ Studies
2020
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Elsholtzia ciliata (Thunb.) Hyl. Extracts from Different Plant Parts: Phenolic Composition, Antioxidant, and Anti-Inflammatory Activities
Journal Article
Elsholtzia ciliata (Thunb.) Hyl. Extracts from Different Plant Parts: Phenolic Composition, Antioxidant, and Anti-Inflammatory Activities
2020
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Overview
Polyphenols play an important role on the health-promoting properties of humans. Plants belonging to Lamiaceae family are known as rich source of phenolic compounds. The current work aimed to evaluate the phenolic compounds, antioxidant, and anti-inflammatory activity of Elsholtzia ciliata (Thunb.) Hyl. ethanolic extracts from leaf, stem, flower, and whole herb. Twelve compounds were identified in ethanolic extracts using high-performance liquid chromatography (HPLC). The HPLC analysis revealed that chlorogenic acid, rosmarinic acid, and rutin were predominant compounds in ethanolicic extracts. Using HPLC-ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) post-column assay, avicularin, chlorogenic, and rosmarinic acids were identified as the predominant radical scavengers in all ethanolic extracts. All tested preparations significantly reduced the level of secretion of proinflammatory cytokines TNF-α, IL-6, and prostaglandin E2 induced by lipopolysaccharide treatment in mouse peritoneal macrophage cell culture. Stem and flower extracts were most efficient in reducing cytokine release, but leaf extract demonstrated stronger effect on prostaglandin E2 secretion. This is the first study exploring antioxidant efficiency by HPLC–ABTS post-column method and investigating anti-inflammatory activity of ethanolic extracts from E. ciliata different plant parts.
Publisher
MDPI AG,MDPI
Subject
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - isolation & purification
/ Anti-Inflammatory Agents - pharmacology
/ Antioxidants - isolation & purification
/ Cell Survival - drug effects
/ Chromatography, High Pressure Liquid
/ Herbs
/ Inflammation Mediators - metabolism
/ Macrophages, Peritoneal - drug effects
/ Macrophages, Peritoneal - metabolism
/ Mice
/ Phenols - isolation & purification
/ Phytochemicals - isolation & purification
/ Phytochemicals - pharmacology
/ Plant Components, Aerial - chemistry
/ Plant Extracts - isolation & purification
/ Plant Extracts - pharmacology
/ Studies
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