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Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
by
Patel, Mahesh J
, Koglin, Joerg
, Armstrong, Paul W
, Ponikowski, Piotr
, Hernandez, Adrian F
, Jia, Gang
, Roessig, Lothar
, Lam, Carolyn S.P
, O’Connor, Christopher M
, Anstrom, Kevin J
, Voors, Adriaan A
, McNulty, Steven E
, Butler, Javed
, Pieske, Burkert
, Ezekowitz, Justin
in
Administration, Oral
/ Aged
/ Binding sites
/ Blood pressure
/ Cardiology and cardiovascular system
/ Cardiovascular Diseases - mortality
/ Chronic Disease
/ Congestive heart failure
/ Death
/ Diuretics
/ Double-Blind Method
/ Ejection fraction
/ Enrollments
/ Female
/ Follow-Up Studies
/ Guanylate cyclase
/ Heart failure
/ Heart Failure - drug therapy
/ Heart Failure - physiopathology
/ Heterocyclic Compounds, 2-Ring - adverse effects
/ Heterocyclic Compounds, 2-Ring - therapeutic use
/ Hospitalization
/ Hospitalization - statistics & numerical data
/ Human health and pathology
/ Humans
/ Hypotension
/ Hypotension - chemically induced
/ Incidence
/ Intravenous administration
/ Life Sciences
/ Male
/ Middle Aged
/ Patient safety
/ Peptides
/ Pyrimidines - adverse effects
/ Pyrimidines - therapeutic use
/ Soluble Guanylyl Cyclase - metabolism
/ Stroke Volume
/ Syncope
/ Syncope - chemically induced
/ Ventricular Dysfunction, Left - drug therapy
2020
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Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
by
Patel, Mahesh J
, Koglin, Joerg
, Armstrong, Paul W
, Ponikowski, Piotr
, Hernandez, Adrian F
, Jia, Gang
, Roessig, Lothar
, Lam, Carolyn S.P
, O’Connor, Christopher M
, Anstrom, Kevin J
, Voors, Adriaan A
, McNulty, Steven E
, Butler, Javed
, Pieske, Burkert
, Ezekowitz, Justin
in
Administration, Oral
/ Aged
/ Binding sites
/ Blood pressure
/ Cardiology and cardiovascular system
/ Cardiovascular Diseases - mortality
/ Chronic Disease
/ Congestive heart failure
/ Death
/ Diuretics
/ Double-Blind Method
/ Ejection fraction
/ Enrollments
/ Female
/ Follow-Up Studies
/ Guanylate cyclase
/ Heart failure
/ Heart Failure - drug therapy
/ Heart Failure - physiopathology
/ Heterocyclic Compounds, 2-Ring - adverse effects
/ Heterocyclic Compounds, 2-Ring - therapeutic use
/ Hospitalization
/ Hospitalization - statistics & numerical data
/ Human health and pathology
/ Humans
/ Hypotension
/ Hypotension - chemically induced
/ Incidence
/ Intravenous administration
/ Life Sciences
/ Male
/ Middle Aged
/ Patient safety
/ Peptides
/ Pyrimidines - adverse effects
/ Pyrimidines - therapeutic use
/ Soluble Guanylyl Cyclase - metabolism
/ Stroke Volume
/ Syncope
/ Syncope - chemically induced
/ Ventricular Dysfunction, Left - drug therapy
2020
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Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
by
Patel, Mahesh J
, Koglin, Joerg
, Armstrong, Paul W
, Ponikowski, Piotr
, Hernandez, Adrian F
, Jia, Gang
, Roessig, Lothar
, Lam, Carolyn S.P
, O’Connor, Christopher M
, Anstrom, Kevin J
, Voors, Adriaan A
, McNulty, Steven E
, Butler, Javed
, Pieske, Burkert
, Ezekowitz, Justin
in
Administration, Oral
/ Aged
/ Binding sites
/ Blood pressure
/ Cardiology and cardiovascular system
/ Cardiovascular Diseases - mortality
/ Chronic Disease
/ Congestive heart failure
/ Death
/ Diuretics
/ Double-Blind Method
/ Ejection fraction
/ Enrollments
/ Female
/ Follow-Up Studies
/ Guanylate cyclase
/ Heart failure
/ Heart Failure - drug therapy
/ Heart Failure - physiopathology
/ Heterocyclic Compounds, 2-Ring - adverse effects
/ Heterocyclic Compounds, 2-Ring - therapeutic use
/ Hospitalization
/ Hospitalization - statistics & numerical data
/ Human health and pathology
/ Humans
/ Hypotension
/ Hypotension - chemically induced
/ Incidence
/ Intravenous administration
/ Life Sciences
/ Male
/ Middle Aged
/ Patient safety
/ Peptides
/ Pyrimidines - adverse effects
/ Pyrimidines - therapeutic use
/ Soluble Guanylyl Cyclase - metabolism
/ Stroke Volume
/ Syncope
/ Syncope - chemically induced
/ Ventricular Dysfunction, Left - drug therapy
2020
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Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
Journal Article
Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
2020
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Overview
Patients with chronic heart failure and a reduced ejection fraction were randomly assigned to the soluble guanylate cyclase stimulator vericiguat or placebo, in addition to guideline-based medical therapy. The incidence of death from cardiovascular causes or first hospitalization for heart failure was lower among patients who received vericiguat.
Publisher
Massachusetts Medical Society
Subject
/ Aged
/ Cardiology and cardiovascular system
/ Cardiovascular Diseases - mortality
/ Death
/ Female
/ Heart Failure - drug therapy
/ Heart Failure - physiopathology
/ Heterocyclic Compounds, 2-Ring - adverse effects
/ Heterocyclic Compounds, 2-Ring - therapeutic use
/ Hospitalization - statistics & numerical data
/ Humans
/ Hypotension - chemically induced
/ Male
/ Peptides
/ Pyrimidines - adverse effects
/ Pyrimidines - therapeutic use
/ Soluble Guanylyl Cyclase - metabolism
/ Syncope
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