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Early versus Late Parenteral Nutrition in Critically Ill Adults
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Early versus Late Parenteral Nutrition in Critically Ill Adults
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Journal Article
Early versus Late Parenteral Nutrition in Critically Ill Adults
2011
Overview
This controlled, randomized, multicenter trial compared early initiation (<2 days) with late initiation (≥8 days) of parenteral nutrition in adults in the intensive care unit. Late initiation was associated with less morbidity and enhanced recovery.
Critical illness induces anorexia and the inability to eat normally, predisposing patients to serious nutritional deficits, muscle wasting, weakness, and delayed recovery. Whether artificial nutritional support improves the outcome for critically ill patients is unclear. The administration route, the time until the initiation of artificial nutrition, the number of calories, and the type of nutrients may be important.
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Enteral nutrition is associated with fewer complications than parenteral nutrition and is less expensive to administer.
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However, the use of enteral nutrition alone often does not achieve caloric targets.
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In addition, underfeeding is associated with weakness, infection,
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an increased duration . . .
Publisher
Massachusetts Medical Society
Subject
/ Aged
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Biological and medical sciences
/ Critical Illness - mortality
/ Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition
/ Female
/ Humans
/ Insulin
/ Length of Stay - statistics & numerical data
/ Male
