Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists

by Fulda, S

in 631/45/612/1243 / 631/80/84/2336 / 692/699/67/322 / Animals / Antagonists / Apoptosis / Apoptosis - drug effects / Apoptosis - physiology / Cell adhesion & migration / Cell Biology / Cell Line, Tumor / Cell migration / Cell Movement - drug effects / Cell Movement - physiology / Cellular control mechanisms / Human Genetics / Humans / IAP protein / Inhibitor of apoptosis proteins / Inhibitor of Apoptosis Proteins - antagonists & inhibitors / Inhibitor of Apoptosis Proteins - physiology / Internal Medicine / Medicine / Medicine & Public Health / Metastases / Metastasis / Neoplasm Metastasis / Neoplasms - drug therapy / Neoplasms - pathology / Oncology / Physiological research / Properties / Proteins / review / Signal Transduction

2014

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists

by Fulda, S

2014

Confirm

Do you wish to request the book?

Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists

by Fulda, S

2014

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists

Fulda, S

2014

Overview

Inhibitor of apoptosis (IAP) proteins are a family comprised of a total of eight mammalian members that were initially described to act as endogenous inhibitors of caspases. In addition, extensive evidence has been accumulated over the last years showing that IAP proteins can regulate various signal transduction pathways, thereby exerting non-apoptotic functions beyond the inhibition of apoptosis. For example, IAP proteins have been implied in the control of cell motility, migration, invasion and metastasis. However, currently the question is controversially discussed whether or not they positively or negatively control these processes. As small-molecule inhibitors of IAP proteins have entered the stage of clinical evaluation as experimental cancer therapeutics, a better understanding of their various cellular effects will be critical for their rational use in the treatment of human diseases.

Share this book

Add to My Shelf

Publisher

Nature Publishing Group UK,Nature Publishing Group

Subject

/ Animals

/ Apoptosis - drug effects