Journal Article

Comprehensive Phytochemical Analysis and Bioactivity Evaluation of Padina boergesenii: Unveiling Its Prospects as a Promising Cosmetic Component

Patel, Nikunj B., Kalasariya, Haresh S., Pereira, Leonel

2023

Overview

Marine macroalgae, such as Padina boergesenii, are gaining recognition in the cosmetics industry as valuable sources of natural bioactive compounds. This study aimed to investigate the biochemical profile of P. boergesenii and evaluate its potential as a cosmetic ingredient. Fourier-transform infrared (FTIR), gas chromatography–mass spectrometry (GCMS), and high-resolution liquid chromatography–mass spectrometry quadrupole time-of-flight (HRLCMS QTOF) analyses were employed to assess the functional groups, phycocompounds, and beneficial compounds present in P. boergesenii. Pigment estimation, total phenol and protein content determination, DPPH antioxidant analysis, and tyrosinase inhibition assay were conducted to evaluate the extracts’ ability to counteract oxidative stress and address hyperpigmentation concerns. Elemental composition and amino acid quantification were determined using inductively coupled plasma atomic emission spectrometry (ICP-AES) and HRLCMS, respectively. FTIR spectroscopy confirmed diverse functional groups, including halo compounds, alcohols, esters, amines, and acids. GCMS analysis identified moisturizing, conditioning, and anti-aging compounds such as long-chain fatty alcohols, fatty esters, fatty acids, and hydrocarbon derivatives. HRLCMS QTOF analysis revealed phenolic compounds, fatty acid derivatives, peptides, terpenoids, and amino acids with antioxidant, anti-inflammatory, and skin-nourishing properties. Elemental analysis indicated varying concentrations of elements, with silicon (Si) being the most abundant and copper (Cu) being the least abundant. The total phenol content was 86.50 µg/mL, suggesting the presence of antioxidants. The total protein content was 113.72 µg/mL, indicating nourishing and rejuvenating effects. The ethanolic extract exhibited an IC50 value of 36.75 μg/mL in the DPPH assay, indicating significant antioxidant activity. The methanolic extract showed an IC50 value of 42.784 μg/mL. Furthermore, P. boergesenii extracts demonstrated 62.14% inhibition of tyrosinase activity. This comprehensive analysis underscores the potential of P. boergesenii as an effective cosmetic ingredient for enhancing skin health. Given the increasing use of seaweed-based bioactive components in cosmetics, further exploration of P. boergesenii’s potential in the cosmetics industry is warranted to leverage its valuable properties.

• Publisher: MDPI AG,MDPI
• Subject: Aging / Aging (natural) / Alcohol / Alcohols / Algae / Amines / Amino acid composition / Amino acids / Analysis / Analytical methods / antioxidant activity / Antioxidants / Antioxidants - analysis / Antioxidants - pharmacology / atomic absorption spectrometry / Bioactive compounds / Biological activity / Chemical composition / Chromatography / Coasts / Copper / Cosmetics / Cosmetics - pharmacology / Cosmetics industry / elemental composition / Esters / Ethanol / Fatty acids / Fourier transform infrared spectroscopy / Fourier transforms / FTIR / Functional groups / Gas chromatography / Gas Chromatography-Mass Spectrometry / GCMS / HRLCMS QTOF / Hyperpigmentation / Inductively coupled plasma / industry / Inflammation / Infrared spectroscopy / ingredients / Liquid chromatography / macroalgae / marine macroalgae / Mass spectrometry / Mass spectroscopy / Monophenol Monooxygenase / Oxidative stress / Padina / Padina boergesenii / Peptides / Phaeophyceae - chemistry / Phenols / Phenols - pharmacology / phytochemicals / Phytochemicals - pharmacology / Plant Extracts - pharmacology / protein content / Proteins / Quadrupoles / R&D / Research & development / Seaweed - chemistry / Seaweeds / Silicon / Skin / Sperm / Terpenes / terpenoids / Tyrosinase