Asset Details
Do you wish to reserve the book?
Detection of Wuchereria bancrofti infection in mosquitoes in areas co-endemic with Brugia malayi in Balasore district, Odisha, India
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Detection of Wuchereria bancrofti infection in mosquitoes in areas co-endemic with Brugia malayi in Balasore district, Odisha, India
Do you wish to request the book?
Detection of Wuchereria bancrofti infection in mosquitoes in areas co-endemic with Brugia malayi in Balasore district, Odisha, India
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Detection of Wuchereria bancrofti infection in mosquitoes in areas co-endemic with Brugia malayi in Balasore district, Odisha, India
2024
Overview
Lymphatic filariasis (LF) is a crippling and disfiguring parasitic condition. India accounts for 55% of the world’s LF burden. The filarial parasite
Wuchereria bancrofti
is known to cause 99.4% of the cases while,
Brugia malayi
accounts for 0.6% of the issue occurring mainly in some pockets of Odisha and Kerala states. The Balasore (Baleswar) district of Odisha has been a known focus of
B. malayi
transmission. We employed molecular xenomonitoring to detect filarial parasite DNA in vectors. In six selected villages, Gravid traps were used to collect
Culex
mosquitoes and hand catch method using aspirators was followed for collection of mansonioides. A total of 2903 mosquitoes comprising of
Cx. quinquefasciatus
(n = 2611; 89.94%),
Cx. tritaeniorhynchus
(n = 100; 3.44%),
Mansonia annuliferea
(n = 139; 4.78%) and
Mansonia uniformis
(n = 53; 1.82%) were collected from six endemic villages. The species wise mosquitoes were made into 118 pools, each with a maximum of 25 mosquitoes, dried and transported to the laboratory at VCRC, Puducherry. The mosquito pools were subjected to parasite DNA extraction, followed by Real-time PCR using LDR and HhaI probes to detect
W. bancrofti
and
B. malayi
infections, respectively. Seven pools (6.66%) of
Cx. quinquefasciatus,
showed infection with only
W. bancrofti
while none of the pools of other mosquito species showed infection with either
W. bancrofti
or
B. malayi.
Although the study area is endemic to
B. malayi
, none of the vectors of
B. malayi
was found with parasite infection. This study highlights the ongoing transmission of bancroftian filariasis in the study villages of Balasore district of Odisha and its implications for evaluating LF elimination programme.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 631/337
/ 692/308
/ 692/699
/ Animals
/ Brugia malayi - isolation & purification
/ DNA
/ Elephantiasis, Filarial - epidemiology
/ Elephantiasis, Filarial - parasitology
/ Elephantiasis, Filarial - transmission
/ Female
/ Humanities and Social Sciences
/ Humans
/ Mosquito Vectors - parasitology
/ Science
/ Vectors
/ Villages
