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Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
by
Kirwan, John P
, Bhatt, Deepak L
, Kashyap, Sangeeta R
, Wolski, Kathy
, Pothier, Claire E
, Brethauer, Stacy A
, Schauer, Philip R
, Nissen, Steven E
, Navaneethan, Sankar D
, Singh, Rishi P
, Aminian, Ali
in
Adult
/ Blood Glucose - analysis
/ Body Mass Index
/ Body weight
/ Cholesterol
/ Cholesterol, HDL - blood
/ Clinical outcomes
/ Clinical trials
/ Combined Modality Therapy
/ Comparative studies
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - drug therapy
/ Diabetes Mellitus, Type 2 - surgery
/ Drug therapy
/ Female
/ Gastrectomy
/ Gastric Bypass
/ Gastrointestinal surgery
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Hemoglobin
/ Humans
/ Hyperglycemia
/ Hypoglycemic Agents - therapeutic use
/ Insulin
/ Insulin - therapeutic use
/ Male
/ Middle Aged
/ Motivation
/ Obesity - complications
/ Obesity - surgery
/ Surgery
/ Treatment Outcome
/ Triglycerides - blood
2017
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Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
by
Kirwan, John P
, Bhatt, Deepak L
, Kashyap, Sangeeta R
, Wolski, Kathy
, Pothier, Claire E
, Brethauer, Stacy A
, Schauer, Philip R
, Nissen, Steven E
, Navaneethan, Sankar D
, Singh, Rishi P
, Aminian, Ali
in
Adult
/ Blood Glucose - analysis
/ Body Mass Index
/ Body weight
/ Cholesterol
/ Cholesterol, HDL - blood
/ Clinical outcomes
/ Clinical trials
/ Combined Modality Therapy
/ Comparative studies
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - drug therapy
/ Diabetes Mellitus, Type 2 - surgery
/ Drug therapy
/ Female
/ Gastrectomy
/ Gastric Bypass
/ Gastrointestinal surgery
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Hemoglobin
/ Humans
/ Hyperglycemia
/ Hypoglycemic Agents - therapeutic use
/ Insulin
/ Insulin - therapeutic use
/ Male
/ Middle Aged
/ Motivation
/ Obesity - complications
/ Obesity - surgery
/ Surgery
/ Treatment Outcome
/ Triglycerides - blood
2017
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Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
by
Kirwan, John P
, Bhatt, Deepak L
, Kashyap, Sangeeta R
, Wolski, Kathy
, Pothier, Claire E
, Brethauer, Stacy A
, Schauer, Philip R
, Nissen, Steven E
, Navaneethan, Sankar D
, Singh, Rishi P
, Aminian, Ali
in
Adult
/ Blood Glucose - analysis
/ Body Mass Index
/ Body weight
/ Cholesterol
/ Cholesterol, HDL - blood
/ Clinical outcomes
/ Clinical trials
/ Combined Modality Therapy
/ Comparative studies
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - drug therapy
/ Diabetes Mellitus, Type 2 - surgery
/ Drug therapy
/ Female
/ Gastrectomy
/ Gastric Bypass
/ Gastrointestinal surgery
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Hemoglobin
/ Humans
/ Hyperglycemia
/ Hypoglycemic Agents - therapeutic use
/ Insulin
/ Insulin - therapeutic use
/ Male
/ Middle Aged
/ Motivation
/ Obesity - complications
/ Obesity - surgery
/ Surgery
/ Treatment Outcome
/ Triglycerides - blood
2017
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Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
Journal Article
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
2017
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Overview
Five-year data showed that among patients with type 2 diabetes and a BMI of 27 to 43, bariatric surgery plus intensive medical therapy was more effective than intensive medical therapy alone in decreasing or resolving hyperglycemia, even among those with a BMI of less than 35.
Observational studies
1
–
6
and randomized, controlled trials, which have generally been short-term studies,
7
–
19
have shown that bariatric surgery, when used specifically to treat diabetes, significantly improves glycemic control and reduces cardiovascular risk factors. In the Surgical Treatment and Medications Potentially Eradicate Diabetes Efficiently (STAMPEDE) trial, we reported that, at 1 year and 3 years after randomization, both gastric bypass and sleeve gastrectomy were superior to intensive medical therapy alone in achieving excellent glycemic control (i.e., glycated hemoglobin ≤6.0%), reducing cardiovascular risk, improving quality of life, and decreasing medication use.
8
–
10
The current article provides results of the final, 5-year . . .
Publisher
Massachusetts Medical Society
Subject
/ Diabetes
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - drug therapy
/ Diabetes Mellitus, Type 2 - surgery
/ Female
/ Glucose
/ Glycated Hemoglobin A - analysis
/ Humans
/ Hypoglycemic Agents - therapeutic use
/ Insulin
/ Male
/ Surgery
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