Journal Article

Electrochemical and Bioelectrochemical Sensing Platforms for Diagnostics of COVID-19

Yamada-Ogatta, Sueli Fumie, Ferreira, Milena do Prado, Teixeira Tarley, César Ricardo

2023

Overview

Rapid transmission and high mortality rates caused by the SARS-CoV-2 virus showed that the best way to fight against the pandemic was through rapid, accurate diagnosis in parallel with vaccination. In this context, several research groups around the world have endeavored to develop new diagnostic methods due to the disadvantages of the gold standard method, reverse transcriptase polymerase chain reaction (RT-PCR), in terms of cost and time consumption. Electrochemical and bioelectrochemical platforms have been important tools for overcoming the limitations of conventional diagnostic platforms, including accuracy, accessibility, portability, and response time. In this review, we report on several electrochemical sensors and biosensors developed for SARS-CoV-2 detection, presenting the concepts, fabrication, advantages, and disadvantages of the different approaches. The focus is devoted to highlighting the recent progress of electrochemical devices developed as next-generation field-deployable analytical tools as well as guiding future researchers in the manufacture of devices for disease diagnosis.

• Publisher: MDPI AG,MDPI
• Subject: biorecognition elements / Biosensing Techniques - methods / Biosensors / Chemical sensors / Coronaviruses / COVID-19 / COVID-19 - diagnosis / COVID-19 diagnostic / COVID-19 Testing / Design and construction / Diagnosis / Diagnostic equipment (Medical) / Electrochemical apparatus / electrochemical methods / Electrochemistry / Engineering research / Fabrication / Humans / Pandemics / Polymerase chain reaction / Review / RNA-directed DNA polymerase / SARS-CoV-2 / Sensors / Severe acute respiratory syndrome coronavirus 2 / Vaccination / Viral diseases