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Effectiveness of Maternal Influenza Immunization in Mothers and Infants
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Effectiveness of Maternal Influenza Immunization in Mothers and Infants
Effectiveness of Maternal Influenza Immunization in Mothers and Infants
Journal Article

Effectiveness of Maternal Influenza Immunization in Mothers and Infants

2008
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Overview
Influenza infection causes significant morbidity in pregnant woman and neonates. In this randomized study of 340 pregnant women in Bangladesh, influenza vaccination during pregnancy was found to decrease laboratory-proven influenza infection in neonates by 63% and febrile respiratory illness in the mothers by more than a third. In pregnant women in Bangladesh, influenza vaccination during pregnancy was found to decrease laboratory-proven influenza infection in neonates by 63% and febrile respiratory illness in the mothers by more than a third. Infection with influenza virus is associated with serious illness and hospitalization among pregnant women 1 – 3 and young infants, including neonates. 4 – 6 Maternal influenza infection has been associated with an increased risk of maternal hospitalization, fetal malformation, and other illnesses. 7 , 8 Influenza infection in young infants often prompts hospitalization and can predispose the infants to bacterial pneumonia or otitis media. 9 , 10 Studies from North America 11 and Hong Kong 12 have shown high rates of hospitalization among infants with influenza, especially those under 6 months of age. 13 The rate of hospitalization for such infants is higher than that for other high-risk groups. A . . .