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A brief history of autophagy from cell biology to physiology and disease
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Journal Article
A brief history of autophagy from cell biology to physiology and disease
2018
Overview
The field of autophagy research has developed rapidly since the first description of the process in the 1960s and the identification of autophagy genes in the 1990s. Autophagy is now increasingly studied at the level of organismal pathophysiology and is being connected to the medical sciences. This Historical Perspective describes a brief history of autophagy and discusses unanswered cell biological questions in the field.
A history of autophagy. In this Perspective, Mizushima describes the leaps and bounds in the history of autophagy and discusses unanswered questions driving the field forward.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
