Journal Article

Manganese cobalt-MOF@carbon nanofiber-based non-enzymatic histamine sensor for the determination of food freshness

Yang, Duck-Joo, Choudhury, Arup, Hossain, SK Safdar, Ahmad, Md. Wasi, Dey, Baban, Kim, Bo Hye, Patra, Chandra N., Kamal, Tahseen

2023

Overview

Early detection of histamine in foodstuffs/beverages could be useful in preventing various diseases. In this work, we have prepared a free-standing hybrid mat based on manganese cobalt (2-methylimodazole)–metal organic frameworks (Mn-Co(2-MeIm)MOF) and carbon nanofibers (CNFs) and explored as a non-enzymatic electrochemical sensor for determining the freshness of fish and bananas based on histamine estimation. As-developed hybrid mat possesses high porosity with a large specific surface area and excellent hydrophilicity those allow easy access of analyte molecules to the redox-active metal sites of MOF. Furthermore, the multiple functional groups of the MOF matrix can act as active adsorption sites for catalysis. The Mn-Co(2-MeIm)MOF@CNF mat-modified GC electrode demonstrated excellent electrocatalytic activities toward the oxidation of histamine under acidic conditions (pH = 5.0) with a faster electron transfer kinetics and superior fouling resistance. The Co(2-MeIm)MOF@CNF/GCE sensor exhibited a wide linear range from 10 to 1500 µM with a low limit of detection (LOD) of 89.6 nM and a high sensitivity of 107.3 µA mM −1  cm −2 . Importantly, as-developed Nb(BTC)MOF@CNF/GCE sensor is enabled to detect histamine in fish and banana samples stored for different periods of time, which thus indicates its practical viability as analytical histamine detector.

• Publisher: Springer Berlin Heidelberg,Springer,Springer Nature B.V
• Subject: Acidic oxides / adsorption / Analytical Chemistry / Animals / Bananas / Beverages / Biochemistry / Biosensors / Carbon / Carbon - chemistry / Carbon fibers / carbon nanofibers / Catalysis / catalytic activity / Characterization and Evaluation of Materials / Chemical properties / Chemical sensors / Chemistry / Chemistry and Materials Science / Cobalt / Cobalt - chemistry / detection limit / Electrochemical Techniques / Electrochemistry / Electrodes / Electron transfer / Fish / Food / Food Science / Freshness / Functional groups / Histamine / hydrophilicity / Laboratory Medicine / Manganese / Measurement / Metal-organic frameworks / Monitoring/Environmental Analysis / Nanofibers / Nanofibers - chemistry / Nanoparticles / Oxidation / Porosity / Research Paper / Sensors / sensors (equipment) / surface area / Testing / viability