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诱导型多能干细胞在神经变性疾病中的作用
by
涂雪松
in
多能干细胞
/ 神经系统疾病
/ 细胞分化
/ 综述
2014
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诱导型多能干细胞在神经变性疾病中的作用
by
涂雪松
in
多能干细胞
/ 神经系统疾病
/ 细胞分化
/ 综述
2014
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Journal Article
诱导型多能干细胞在神经变性疾病中的作用
2014
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Overview
诱导型多能干细胞技术是一种通过新的体细胞重编程,将组织细胞转化为可多向分化的细胞即干细胞的技术。目前已将4种转录因子导入人体皮肤纤维母细胞,并首次成功诱导出诱导型多能干细胞。此项技术不但可以建立神经系统疾病动物模型,用于发病机制和致病基因的研究,而且可以开展移植研究,验证疗效及筛选药物。
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