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Hepatitis A: Epidemiology, High-Risk Groups, Prevention and Research on Antiviral Treatment
by
Izopet, Jacques
, Migueres, Marion
, Lhomme, Sébastien
in
Age
/ Antibodies
/ Antiviral agents
/ Antiviral Agents - pharmacology
/ Antiviral Agents - therapeutic use
/ Antiviral drugs
/ Asymptomatic
/ direct contact
/ Disease
/ Disease Outbreaks - prevention & control
/ disease severity
/ Epidemiology
/ Food contamination
/ Food contamination & poisoning
/ globalization
/ Hepatitis A
/ Hepatitis A - drug therapy
/ Hepatitis A - epidemiology
/ Hepatitis A - prevention & control
/ Hepatitis A virus - drug effects
/ Hepatovirus A
/ high-risk groups
/ Homeless people
/ homelessness
/ Homosexuality, Male
/ Human health and pathology
/ Humans
/ Incidence
/ Industrialized nations
/ Infections
/ Infectious diseases
/ Life Sciences
/ Male
/ Medical research
/ men who have sex with men
/ Outbreaks
/ people who use substances
/ Review
/ Risk Factors
/ Risk groups
/ RNA polymerase
/ Sanitation
/ Sexual and Gender Minorities
/ Socioeconomic factors
/ Travel
/ Travellers
/ vaccination
/ Viruses
/ water pollution
2021
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Hepatitis A: Epidemiology, High-Risk Groups, Prevention and Research on Antiviral Treatment
by
Izopet, Jacques
, Migueres, Marion
, Lhomme, Sébastien
in
Age
/ Antibodies
/ Antiviral agents
/ Antiviral Agents - pharmacology
/ Antiviral Agents - therapeutic use
/ Antiviral drugs
/ Asymptomatic
/ direct contact
/ Disease
/ Disease Outbreaks - prevention & control
/ disease severity
/ Epidemiology
/ Food contamination
/ Food contamination & poisoning
/ globalization
/ Hepatitis A
/ Hepatitis A - drug therapy
/ Hepatitis A - epidemiology
/ Hepatitis A - prevention & control
/ Hepatitis A virus - drug effects
/ Hepatovirus A
/ high-risk groups
/ Homeless people
/ homelessness
/ Homosexuality, Male
/ Human health and pathology
/ Humans
/ Incidence
/ Industrialized nations
/ Infections
/ Infectious diseases
/ Life Sciences
/ Male
/ Medical research
/ men who have sex with men
/ Outbreaks
/ people who use substances
/ Review
/ Risk Factors
/ Risk groups
/ RNA polymerase
/ Sanitation
/ Sexual and Gender Minorities
/ Socioeconomic factors
/ Travel
/ Travellers
/ vaccination
/ Viruses
/ water pollution
2021
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Hepatitis A: Epidemiology, High-Risk Groups, Prevention and Research on Antiviral Treatment
by
Izopet, Jacques
, Migueres, Marion
, Lhomme, Sébastien
in
Age
/ Antibodies
/ Antiviral agents
/ Antiviral Agents - pharmacology
/ Antiviral Agents - therapeutic use
/ Antiviral drugs
/ Asymptomatic
/ direct contact
/ Disease
/ Disease Outbreaks - prevention & control
/ disease severity
/ Epidemiology
/ Food contamination
/ Food contamination & poisoning
/ globalization
/ Hepatitis A
/ Hepatitis A - drug therapy
/ Hepatitis A - epidemiology
/ Hepatitis A - prevention & control
/ Hepatitis A virus - drug effects
/ Hepatovirus A
/ high-risk groups
/ Homeless people
/ homelessness
/ Homosexuality, Male
/ Human health and pathology
/ Humans
/ Incidence
/ Industrialized nations
/ Infections
/ Infectious diseases
/ Life Sciences
/ Male
/ Medical research
/ men who have sex with men
/ Outbreaks
/ people who use substances
/ Review
/ Risk Factors
/ Risk groups
/ RNA polymerase
/ Sanitation
/ Sexual and Gender Minorities
/ Socioeconomic factors
/ Travel
/ Travellers
/ vaccination
/ Viruses
/ water pollution
2021
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Hepatitis A: Epidemiology, High-Risk Groups, Prevention and Research on Antiviral Treatment
Journal Article
Hepatitis A: Epidemiology, High-Risk Groups, Prevention and Research on Antiviral Treatment
2021
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Overview
The hepatitis A virus (HAV) is a leading cause of acute viral hepatitis worldwide. It is transmitted mainly by direct contact with patients who have been infected or by ingesting contaminated water or food. The virus is endemic in low-income countries where sanitary and sociodemographic conditions are poor. Paradoxically, improving sanitary conditions in these countries, which reduces the incidence of HAV infections, can lead to more severe disease in susceptible adults. The populations of developed countries are highly susceptible to HAV, and large outbreaks can occur when the virus is spread by globalization and by increased travel and movement of foodstuffs. Most of these outbreaks occur among high-risk groups: travellers, men who have sex with men, people who use substances, and people facing homelessness. Hepatitis A infections can be prevented by vaccination; safe and effective vaccines have been available for decades. Several countries have successfully introduced universal mass vaccination for children, but high-risk groups in high-income countries remain insufficiently protected. The development of HAV antivirals may be important to control HAV outbreaks in developed countries where a universal vaccination programme is not recommended.
Publisher
MDPI AG,MDPI
Subject
/ Antiviral Agents - pharmacology
/ Antiviral Agents - therapeutic use
/ Disease
/ Disease Outbreaks - prevention & control
/ Food contamination & poisoning
/ Hepatitis A - prevention & control
/ Hepatitis A virus - drug effects
/ Humans
/ Male
/ Review
/ Sexual and Gender Minorities
/ Travel
/ Viruses
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