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Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data

by Dekker, Cornelia L. , Gurwith, Marc , Polack, Fernando P. , Ward, Brian J. , Lambert, Paul Henri , Perlman, Stanley , Didierlaurent, Arnaud M. , Law, Barbara , Cramer, Jakob P. , Van Braeckel, Eva , Spergel, Jonathan M. , Dudley, Matthew Z. , Graham, Barney S. , Munoz, Flor M.

in Adverse event / Allergy and Immunology / Antibodies / Asymptomatic / Case definition / Clinical trials / Collaboration / Coronaviruses / COVID-19 / COVID-19 Vaccines / Data Collection / Enhanced disease / Epidemics / Guidelines / Humans / Illnesses / Immunization / Immunization - adverse effects / Infections / Influenza / Laboratories / Literature reviews / Measles / Middle East respiratory syndrome / Pandemics / Pathogenesis / Pathogens / Respiratory / Respiratory diseases / Respiratory syncytial virus / Review / SARS-CoV-2 / Severe acute respiratory syndrome coronavirus 2 / Surveillance / Systemic disease / Systemic diseases / Vaccine / Vaccines / Vaccines - adverse effects / Viral diseases / Viruses / Working groups

2021

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Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data

2021

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2021

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Journal Article

Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data

Dekker, Cornelia L.,

Gurwith, Marc,

Polack, Fernando P.,

Ward, Brian J.,

Lambert, Paul Henri,

Perlman, Stanley,

Didierlaurent, Arnaud M.,

Law, Barbara,

Cramer, Jakob P.,

Van Braeckel, Eva,

Spergel, Jonathan M.,

Dudley, Matthew Z.,

Graham, Barney S.,

Munoz, Flor M.

2021

Overview

This is a Brighton Collaboration Case Definition of the term “Vaccine Associated Enhanced Disease” to be utilized in the evaluation of adverse events following immunization. The Case Definition was developed by a group of experts convened by the Coalition for Epidemic Preparedness Innovations (CEPI) in the context of active development of vaccines for SARS-CoV-2 vaccines and other emerging pathogens. The case definition format of the Brighton Collaboration was followed to develop a consensus definition and defined levels of certainty, after an exhaustive review of the literature and expert consultation. The document underwent peer review by the Brighton Collaboration Network and by selected Expert Reviewers prior to submission.

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Publisher

Elsevier Ltd,Elsevier Limited,The Author(s). Published by Elsevier Ltd

Subject

Adverse event

/ Allergy and Immunology