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Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil
by
Maki, K C
, Kelley, K M
, Kaden, V N
, Palacios, O M
, Geiger, C J
, Dicklin, M R
, Lawless, A L
in
13/56
/ 692/699/75/2099
/ 692/700/2814
/ Apolipoprotein A-I - blood
/ Apolipoproteins - blood
/ Apolipoproteins B - blood
/ Blood lipoproteins
/ Cardiovascular diseases
/ Cholesterol
/ Cholesterol - blood
/ Clinical Nutrition
/ Comparative analysis
/ Corn
/ Corn oil
/ Corn Oil - administration & dosage
/ Cross-Over Studies
/ Double-Blind Method
/ Eating - physiology
/ Epidemiology
/ Fatty acids
/ Female
/ Health aspects
/ Health risks
/ Humans
/ Internal Medicine
/ Lipoproteins
/ Lipoproteins - blood
/ Lipoproteins, LDL - blood
/ Male
/ Medicine
/ Medicine & Public Health
/ Metabolic Diseases
/ Middle Aged
/ Olive oil
/ Olive Oil - administration & dosage
/ original-article
/ Proteolipids
/ Public Health
/ Studies
/ Vegetable oils
2017
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Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil
by
Maki, K C
, Kelley, K M
, Kaden, V N
, Palacios, O M
, Geiger, C J
, Dicklin, M R
, Lawless, A L
in
13/56
/ 692/699/75/2099
/ 692/700/2814
/ Apolipoprotein A-I - blood
/ Apolipoproteins - blood
/ Apolipoproteins B - blood
/ Blood lipoproteins
/ Cardiovascular diseases
/ Cholesterol
/ Cholesterol - blood
/ Clinical Nutrition
/ Comparative analysis
/ Corn
/ Corn oil
/ Corn Oil - administration & dosage
/ Cross-Over Studies
/ Double-Blind Method
/ Eating - physiology
/ Epidemiology
/ Fatty acids
/ Female
/ Health aspects
/ Health risks
/ Humans
/ Internal Medicine
/ Lipoproteins
/ Lipoproteins - blood
/ Lipoproteins, LDL - blood
/ Male
/ Medicine
/ Medicine & Public Health
/ Metabolic Diseases
/ Middle Aged
/ Olive oil
/ Olive Oil - administration & dosage
/ original-article
/ Proteolipids
/ Public Health
/ Studies
/ Vegetable oils
2017
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Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil
by
Maki, K C
, Kelley, K M
, Kaden, V N
, Palacios, O M
, Geiger, C J
, Dicklin, M R
, Lawless, A L
in
13/56
/ 692/699/75/2099
/ 692/700/2814
/ Apolipoprotein A-I - blood
/ Apolipoproteins - blood
/ Apolipoproteins B - blood
/ Blood lipoproteins
/ Cardiovascular diseases
/ Cholesterol
/ Cholesterol - blood
/ Clinical Nutrition
/ Comparative analysis
/ Corn
/ Corn oil
/ Corn Oil - administration & dosage
/ Cross-Over Studies
/ Double-Blind Method
/ Eating - physiology
/ Epidemiology
/ Fatty acids
/ Female
/ Health aspects
/ Health risks
/ Humans
/ Internal Medicine
/ Lipoproteins
/ Lipoproteins - blood
/ Lipoproteins, LDL - blood
/ Male
/ Medicine
/ Medicine & Public Health
/ Metabolic Diseases
/ Middle Aged
/ Olive oil
/ Olive Oil - administration & dosage
/ original-article
/ Proteolipids
/ Public Health
/ Studies
/ Vegetable oils
2017
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Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil
Journal Article
Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil
2017
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Overview
Background:
Corn oil (CO) and extra-virgin olive oil (EVOO) are rich sources of unsaturated fatty acids (UFA), but UFA profiles differ among oils, which may affect lipoprotein levels.
Objectives:
The objective of this study was to assess the effects of CO versus EVOO intake on fasting lipoprotein and subfraction cholesterol levels, apolipoprotein (apo) A1, apo B, and low-density lipoprotein particle concentrations in men and women.
Subjects/Methods:
As part of a weight maintenance diet, men and women were provided with food items prepared with 54 g per day of CO or EVOO (21-day treatment, 21-day washout) in a randomized, double-blind, controlled-feeding, crossover trial. Fasting lipoprotein cholesterol and related variables were determined with density gradient ultracentrifugation.
Results:
Among the 54 completers, CO reduced total cholesterol, low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), apo B and LDL particle concentration to a greater extent compared with EVOO intake. Changes in LDL-C and VLDL-C contributed to the larger reduction in non-HDL-C with CO compared with EVOO intake (−0.39 mmol/l vs −0.04 mmol/l;
P
<0.001). The larger reduction in LDL-C by CO intake was attributable to changes (
P
<0.05) caused by CO vs EVOO in large LDL
1+2
-C (−0.22 mmol/l) and intermediate-density lipoprotein cholesterol (−0.12 mmol/l). HDL-C responses did not differ between treatments, but apo A1 increased more with EVOO compared with CO intake (4.6 versus 0.7 mg/dl, respectively,
P
=0.016).
Conclusions:
CO intake reduced atherogenic lipoprotein cholesterol and particle concentrations to a larger extent than did EVOO, which may have implications for cardiovascular disease risk.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
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