Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Mortality in sea lions is associated with the introduction of the H5N1 clade 2.3.4.4b virus in Brazil October 2023: whole genome sequencing and phylogenetic analysis

by Macagnan, Eduardo , Silva, Laura Morais Nascimento , de Carvalho Araujo, Andreina , Cho, Andrew Yong , Arns, Clarice Weis , Malta, Fernanda , Kolesnikvoas, Cristiane K. M. , Dick, Jeferson Luis , Albuquerque, Adriana Silva , Miller, Michael , Pinho, João Renato R. , Lemos, Giulia Gaglianone , Amgarten, Deyvid , Vieira, Jenyffer Vierheller , Lee, Dong-Hun , de Souza, Gabriela Cristini , Corrêa, Thais Camilo , Ferreira, Helena Lage , de Castilho, Pedro Volkmer , Palameta, Soledad , Meurer, Rafael , Barreto, André Silva , Lee, Sun-Hak , Groch, Karina Rejane , Dorlass, Erick G. , Durigon, Edison L.

in Adaptation / Amino acids / Analysis / Animals / Avian flu / Avian influenza / Avian influenza viruses / Birds / Brazil / Diseases / DNA sequencing / Evolution / Genes / Genetic analysis / Genetic aspects / Genetic diversity / Genetic Variation / genome / Genome, Viral / Genomes / Genomic analysis / Genomics / Genotype / Genotype & phenotype / Genotypes / Health aspects / High pathogenicity avian influenza / Influenza A virus / Influenza A Virus, H5N1 Subtype - classification / Influenza A Virus, H5N1 Subtype - genetics / landscape genetics / mammals / Marine mammal / Marine mammals / Medicine / Medicine & Public Health / Methods / Mortality / Mutation / North America / Nucleotide sequencing / Orthomyxoviridae Infections - veterinary / Orthomyxoviridae Infections - virology / Otariidae / Phylogenetics / Phylogeny / Public health / Sea lions / Sea Lions - virology / Software / South America / Transgenics / Veterinary Medicine/Veterinary Science / Virus / Viruses / Whole Genome Sequencing / Zoology / Zoonotic diseases

2024

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Mortality in sea lions is associated with the introduction of the H5N1 clade 2.3.4.4b virus in Brazil October 2023: whole genome sequencing and phylogenetic analysis

2024

Confirm

Do you wish to request the book?

Mortality in sea lions is associated with the introduction of the H5N1 clade 2.3.4.4b virus in Brazil October 2023: whole genome sequencing and phylogenetic analysis

2024

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Mortality in sea lions is associated with the introduction of the H5N1 clade 2.3.4.4b virus in Brazil October 2023: whole genome sequencing and phylogenetic analysis

Macagnan, Eduardo,

Silva, Laura Morais Nascimento,

de Carvalho Araujo, Andreina,

Cho, Andrew Yong,

Arns, Clarice Weis,

Malta, Fernanda,

Kolesnikvoas, Cristiane K. M.,

Dick, Jeferson Luis,

Albuquerque, Adriana Silva,

Miller, Michael,

Pinho, João Renato R.,

Lemos, Giulia Gaglianone,

Amgarten, Deyvid,

Vieira, Jenyffer Vierheller,

Lee, Dong-Hun,

de Souza, Gabriela Cristini,

Corrêa, Thais Camilo,

Ferreira, Helena Lage,

de Castilho, Pedro Volkmer,

Palameta, Soledad,

Meurer, Rafael,

Barreto, André Silva,

Lee, Sun-Hak,

Groch, Karina Rejane,

Dorlass, Erick G.,

Durigon, Edison L.

2024

Overview

Clade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 virus was detected in the South American sea lions found dead in Santa Catarina, Brazil, in October 2023. Whole genome sequencing and comparative phylogenetic analysis were conducted to investigate the origin, genetic diversity, and zoonotic potentials of the H5N1 viruses. The H5N1 viruses belonged to the genotype B3.2 of clade 2.3.4.4b H5N1 virus, which was identified in North America and disseminated to South America. They have acquired new amino acid substitutions related to mammalian host affinity. Our study provides insights into the genetic landscape of HPAI H5N1 viruses in Brazil, highlighting the continuous evolutionary processes contributing to their possible adaptation to mammalian hosts.

Share this book

Add to My Shelf

Publisher

BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC

Subject

/ Animals

/ Avian influenza viruses