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Gut microbiome and its role in colorectal cancer
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Journal Article
Gut microbiome and its role in colorectal cancer
2021
Overview
Colorectal cancer (CRC) is still one of the most common types of cancer in the world, and the gut microbiome plays an important role in its development. The microbiome is involved in the carcinogenesis, formation and progression of CRC as well as its response to different systemic therapies. The composition of bacterial strains and the influence of geography, race, sex, and diet on the composition of the microbiome serve as important information for screening, early detection and prediction of the treatment outcome of CRC.
Microbiome modulation is one of the most prospective new strategies in medicine to improve the health of individuals. Therefore, future research and clinical trials on the gut microbiome in oncology as well as in the treatment of CRC patients are warranted to determine the efficacy of systemic treatments for CRC, minimize adverse effects and increase survival rates.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Analysis
/ Bacteria
/ Biomedical and Life Sciences
/ Cancer
/ Diet
/ Health Promotion and Disease Prevention
/ Humans
/ Identification and classification
/ Microbiota (Symbiotic organisms)
/ Modulation of gut microbiome
/ Mutation
/ Obesity
/ Oncology
/ Prognostic and predictive biomarkers
/ Review
