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Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection
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Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection
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Journal Article
Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection
2020
Overview
Kirtsman et al discuss the probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection. They present a case study of a 40-year-old woman who was admitted to a tertiary hospital in Toronto, Ontario. She had familial neutropenia, gestational diabetes and a history of frequent bacterial infections during pregnancy, which resolved with antibiotic treatment. Details of the maternal course and outcome have been published separately because of her hematologic condition. A nasopharyngeal swab was positive for suspected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gene targets via reverse transcription polymerase chain reaction (RT-PCR) testing. There were no fetal concerns during the pregnancy or following admission. A semiurgent cesarean delivery was done under regional anesthesia, with airborne, droplet and contact precautions, owing to worsening coagulopathy and reducing platelet count at 35 weeks. Artificial rupture of membranes was performed at operation. The male neonate was vigorous and did not require resuscitation. His Apgar scores were 9 at 1 minute and 9 at 5 minutes, but all 3 of the neonate's nasopharyngeal swabs were positive for SARS-CoV-2 gene targets via RT-PCR testing.
Publisher
Elsevier Inc,CMA Impact Inc,Joule Inc,CMA Impact, Inc
Subject
/ Clinical Laboratory Techniques
/ Coronavirus Infections - congenital
/ Coronavirus Infections - diagnosis
/ Coronavirus Infections - transmission
/ COVID-19
/ Enzymes
/ Female
/ Genes
/ Glucose
/ Humans
/ Infectious Disease Transmission, Vertical
/ Male
/ Placenta
/ Pneumonia, Viral - congenital
/ Pneumonia, Viral - diagnosis
/ Pneumonia, Viral - transmission
/ Practice
/ Pregnancy Complications, Infectious
/ Reverse Transcriptase Polymerase Chain Reaction
/ Severe acute respiratory syndrome
/ Severe acute respiratory syndrome coronavirus 2
/ Skin
/ Vagina
