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Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells

by López Larrea, Carlos , Cibelli, Jose B , Ortega Suárez, Francisco José , Blanco Gelaz, Miguel Ángel , Fernández Fraga, Mario , Suárez Álvarez, Beatriz , Suhr, Steve T , Calvanese, Vincenzo , Otero Hernández, Jesús , Rodríguez López, Ramón María , Moore, Harry

in Antigen Presentation / Antigen processing / B cells / Bisulfite / Cell Biology / Cell Biology/Gene Expression / Cell surface / Chromatin / Deoxyribonucleic acid / Development strategies / DNA / DNA methylation / Embryo cells / Embryonic stem cells / Embryonic Stem Cells - immunology / Embryos / Epigenesis, Genetic / Epigenetic inheritance / Epigenetics / Gene expression / Gene regulation / Gene sequencing / Genes / Genetics and Genomics/Epigenetics / Health aspects / Histocompatibility antigen HLA / Histocompatibility Antigens / Histocompatibility Antigens Class I / Histocompatibility Antigens Class II / HLA antigens / Humans / Immune response / Immune system / Immunity / Immunogenicity / Immunological tolerance / Immunology/Antigen Processing and Recognition / Immunology/Immunomodulation / Immunoprecipitation / Induced Pluripotent Stem Cells - immunology / Ligands / Lymphocytes B / Major histocompatibility complex / Methylation / MICA protein / Neurotrophin 2 / Peptides / Pluripotency / Regeneration / Stem cell transplantation / Stem cells / Sulfites / TAP protein / Tapasin / Teratocarcinoma / Tissue engineering

2010

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Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells

2010

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Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells

2010

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Journal Article

Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells

López Larrea, Carlos,

Cibelli, Jose B,

Ortega Suárez, Francisco José,

Blanco Gelaz, Miguel Ángel,

Fernández Fraga, Mario,

Suárez Álvarez, Beatriz,

Suhr, Steve T,

Calvanese, Vincenzo,

Otero Hernández, Jesús,

Rodríguez López, Ramón María,

Moore, Harry

2010

Overview

We thank Cristina B. Mendoza for excellent technical assistance and Dr.Peter Andrews for providing us reagents. Conceived and designed the experiments: BS MFF CLL. Performed the experiments: BS VC STS. Analyzed the data: BS RMR MABG CLL. Contributed reagents/materials/analysis tools: RMR FO JO JC HM. Wrote the paper: BS HM MFF CLL.

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Publisher

Public Library of Science,Public Library of Science (PLoS)

Subject

/ B cells

/ Cell Biology/Gene Expression

/ Cell surface