Asset Details
Do you wish to reserve the book?
Breaking Patterns of Environmentally Influenced Disease for Health Risk Reduction: Immune Perspectives
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Breaking Patterns of Environmentally Influenced Disease for Health Risk Reduction: Immune Perspectives
Do you wish to request the book?
Breaking Patterns of Environmentally Influenced Disease for Health Risk Reduction: Immune Perspectives
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Breaking Patterns of Environmentally Influenced Disease for Health Risk Reduction: Immune Perspectives
2010
Overview
Background: Diseases rarely, if ever, occur in isolation. Instead, most represent part of a more complex web or \"pattern\" of conditions that are connected via underlying biological mechanisms and processes, emerge across a lifetime, and have been identified with the aid of large medical databases. Objective: We have described how an understanding of patterns of disease may be used to develop new strategies for reducing the prevalence and risk of major immune-based illnesses and diseases influenced by environmental stimuli. Findings: Examples of recently defined patterns of diseases that begin in childhood include not only metabolic syndrome, with its characteristics of inflammatory dysregulation, but also allergic, autoimmune, recurrent infection, and other inflammatory patterns of disease. The recent identification of major immune-based disease patterns beginning in childhood suggests that the immune system may play an even more important role in determining health status and health care needs across a lifetime than was previously understood. Conclusions: Focusing on patterns of disease, as opposed to individual conditions, offers two important venues for environmental health risk reduction. First, prevention of developmental immunotoxicity and pediatric immune dysfunction can be used to act against multiple diseases. Second, pattern-based treatment of entryway diseases can be tailored with the aim of disrupting the entire disease pattern and reducing the risk of later-life illnesses connected to underlying immune dysfunction. Disease-pattern–based evaluation, prevention, and treatment will require a change from the current approach for both immune safety testing and pediatric disease management.
Publisher
National Institute of Environmental Health Sciences,Environmental Health Perspectives,US Department of Health and Human Services
Subject
/ Biological and medical sciences
/ Child
/ Chronic obstructive pulmonary disease, asthma
/ developmental immunotoxicity
/ Diabetes
/ Environment. Living conditions
/ Environmental Exposure - prevention & control
/ Environmental Pollutants - toxicity
/ Focusing
/ Health
/ Humans
/ Immune System Diseases - chemically induced
/ Immune System Diseases - complications
/ Immune System Diseases - prevention & control
/ Metabolic Diseases - chemically induced
/ Metabolic Diseases - complications
/ Metabolic Diseases - immunology
/ Public health. Hygiene-occupational medicine
/ Review
/ Reviews
/ Risk
/ Stimuli
/ Strategy
