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Emergence of Difficult-to-Treat Tinea Corporis Caused by Trichophyton mentagrophytes Complex Isolates, Paris, France

by Mingui, Anselme , Bagot, Martine , Gits-Muselli, Maud , Gabison, Germaine , Hamane, Samia , Petit, Antoine , Bretagne, Stéphane , Benderdouche, Mazouz , Alanio, Alexandre , Dellière, Sarah , Joannard, Brune

in Antifungal agents / Antifungal Agents - pharmacology / Antifungal Agents - therapeutic use / antimicrobial resistance / Arthrodermataceae / Athletes foot / Causes of / Complex Isolates, Paris, France / Dermatophytes / Dispatch / Drug resistance in microorganisms / Drug Resistance, Fungal / Drug therapy / Drugs / Emergence of Difficult-to-Treat Tinea Corporis Caused by / France - epidemiology / Fungal infections / Genetic aspects / Humans / Identification and classification / Life Sciences / Mutation / Original Research / Paris / Patients / Ringworm / skin infections / squalene epoxidase / Steroids / terbinafine / Tinea - diagnosis / Tinea - drug therapy / Trichophyton - genetics / Trichophyton indotineae / Trichophyton mentagrophytes complex

2022

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Emergence of Difficult-to-Treat Tinea Corporis Caused by Trichophyton mentagrophytes Complex Isolates, Paris, France

2022

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Emergence of Difficult-to-Treat Tinea Corporis Caused by Trichophyton mentagrophytes Complex Isolates, Paris, France

2022

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Journal Article

Emergence of Difficult-to-Treat Tinea Corporis Caused by Trichophyton mentagrophytes Complex Isolates, Paris, France

Mingui, Anselme,

Bagot, Martine,

Gits-Muselli, Maud,

Gabison, Germaine,

Hamane, Samia,

Petit, Antoine,

Bretagne, Stéphane,

Benderdouche, Mazouz,

Alanio, Alexandre,

Dellière, Sarah,

Joannard, Brune

2022

Overview

We describe 7 cases of extensive tinea corporis since 2018 in a hospital in Paris, France, after failure to cure with terbinafine. Molecular analysis indicated Trichophyton mentagrophytes internal transcribed spacer type VIII (T. indotineae). This strain, which has mutations in the squalene epoxidase gene, is spreading on the Indian subcontinent.

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Publisher

U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention

Subject

Antifungal agents

/ Antifungal Agents - pharmacology

/ Antifungal Agents - therapeutic use

/ antimicrobial resistance

/ Arthrodermataceae

/ Athletes foot

/ Causes of