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Phase 2b Controlled Trial of M72/AS01E Vaccine to Prevent Tuberculosis

by Nduba, Videlis , Martinson, Neil , Ayles, Helen M , Bollaerts, Anne , Van Brakel, Elana , Henostroza, German , Khatoon Azam, Aisha , Wilkinson, Robert J , Van Der Meeren, Olivier , Thienemann, Friedrich , Muyoyeta, Monde , Scriba, Thomas J , Tait, Dereck R , Diacon, Andreas , Singh, Tina , Ginsberg, Ann M , Hellström, Elizabeth , Gillard, Paul , Blatner, Gretta L , Evans, Thomas G , Tameris, Michele , Akite, Elaine J , Hatherill, Mark , Malahleha, Mookho , Innes, James C , Demoitié, Marie-Ange

in Antigens / Clinical medicine / Clinical trials / HIV / Human immunodeficiency virus / Influenza / Information sharing / Injection / Interferon / Lung diseases / Population / Sputum / Tuberculosis / Vaccine efficacy / Vaccines

2018

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Phase 2b Controlled Trial of M72/AS01E Vaccine to Prevent Tuberculosis

2018

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Phase 2b Controlled Trial of M72/AS01E Vaccine to Prevent Tuberculosis

2018

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Journal Article

Phase 2b Controlled Trial of M72/AS01E Vaccine to Prevent Tuberculosis

Nduba, Videlis,

Martinson, Neil,

Ayles, Helen M,

Bollaerts, Anne,

Van Brakel, Elana,

Henostroza, German,

Khatoon Azam, Aisha,

Wilkinson, Robert J,

Van Der Meeren, Olivier,

Thienemann, Friedrich,

Muyoyeta, Monde,

Scriba, Thomas J,

Tait, Dereck R,

Diacon, Andreas,

Singh, Tina,

Ginsberg, Ann M,

Hellström, Elizabeth,

Gillard, Paul,

Blatner, Gretta L,

Evans, Thomas G,

Tameris, Michele,

Akite, Elaine J,

Hatherill, Mark,

Malahleha, Mookho,

Innes, James C,

Demoitié, Marie-Ange

2018

Overview

Mycobacterium tuberculosis is a major global pathogen. In this trial in sub-Saharan Africa, a new vaccine was found to have 54% efficacy against the development of active pulmonary M. tuberculosis in infected adults.

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Publisher

Massachusetts Medical Society

Subject

Antigens

/ Clinical medicine

/ Clinical trials

/ HIV

/ Human immunodeficiency virus

/ Influenza

/ Information sharing