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Remdesivir for 5 or 10 Days in Patients with Severe Covid-19

by SenGupta, Devi , Goldman, Jason D , Marty, Francisco M , Diaz, George , Spinner, Christoph D , Lye, David C.B , Towner, William J , Osinusi, Anu O , Ahn, Mi-Young , Blair, Christiana , Mullane, Kathleen M , Hui, David S , Galli, Massimo , Chen, Yao-Shen , Montejano, Rocio , Muñoz, Jose , Hyland, Robert H , Wei, Xuelian , Brainard, Diana M , Tashima, Karen T , Gaggar, Anuj , Subramanian, Aruna , Nahass, Ronald G , Cao, Huyen , Marks, Kristen M , Bruno, Raffaele

in Adenosine Monophosphate - administration & dosage / Adenosine Monophosphate - adverse effects / Adenosine Monophosphate - analogs & derivatives / Adult / Aged / Alanine / Alanine - administration & dosage / Alanine - adverse effects / Alanine - analogs & derivatives / Alanine transaminase / Animal models / Antiviral activity / Antiviral Agents - administration & dosage / Antiviral Agents - adverse effects / Antiviral drugs / Betacoronavirus / Confidence intervals / Constipation / Coronavirus Infections - drug therapy / Coronavirus Infections - mortality / Coronavirus Infections - therapy / Coronaviruses / COVID-19 / Creatinine / Disease / DNA-directed RNA polymerase / Drug Administration Schedule / Female / Hospitalization / Humans / Intravenous administration / Male / Mechanical ventilation / Middle Aged / Nausea / Original / Oxygen Inhalation Therapy / Pandemics / Patients / Pneumonia, Viral - drug therapy / Pneumonia, Viral - mortality / Pneumonia, Viral - therapy / Respiratory failure / SARS-CoV-2 / Severe acute respiratory syndrome coronavirus 2 / Treatment Outcome

2020

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Remdesivir for 5 or 10 Days in Patients with Severe Covid-19

2020

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Remdesivir for 5 or 10 Days in Patients with Severe Covid-19

2020

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Journal Article

Remdesivir for 5 or 10 Days in Patients with Severe Covid-19

SenGupta, Devi,

Goldman, Jason D,

Marty, Francisco M,

Diaz, George,

Spinner, Christoph D,

Lye, David C.B,

Towner, William J,

Osinusi, Anu O,

Ahn, Mi-Young,

Blair, Christiana,

Mullane, Kathleen M,

Hui, David S,

Galli, Massimo,

Chen, Yao-Shen,

Montejano, Rocio,

Muñoz, Jose,

Hyland, Robert H,

Wei, Xuelian,

Brainard, Diana M,

Tashima, Karen T,

Gaggar, Anuj,

Subramanian, Aruna,

Nahass, Ronald G,

Cao, Huyen,

Marks, Kristen M,

Bruno, Raffaele

2020

Overview

A randomized trial comparing a 5-day course of intravenous remdesivir with a 10-day course in patients with Covid-19 pneumonia and hypoxemia who were not yet receiving mechanical ventilation showed no significant differences in outcome related to the duration of treatment.

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Publisher

Massachusetts Medical Society

Subject

Adenosine Monophosphate - administration & dosage

/ Adenosine Monophosphate - adverse effects

/ Adenosine Monophosphate - analogs & derivatives

/ Adult

/ Aged

/ Alanine

/ Alanine - administration & dosage