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Making innate sense of mRNA vaccine adjuvanticity
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Journal Article
Making innate sense of mRNA vaccine adjuvanticity
2022
Overview
mRNA vaccines such as those used to prevent COVID-19 owe part of their success to methylation that masks immunostimulatory properties of the mRNA, but the immunological mechanisms of adjuvanticity are unclear. Two new studies reveal distinct mechanisms for innate sensing of this hidden adjuvant.
