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Objectives: Micro-pulse cyclophotocoagulation (MP-CPC) represents the latest iteration of minimally invasive laser procedures aimed at reducing intraocular pressure (IOP) through the disruption of pigmented ciliary body epithelium. This systematic review aims to assess the efficacy and safety profile of the MP-CPC procedure in comparison to CW-CPC for the treatment of glaucoma. Methods: We initiated a search on PubMed, ScienceDirect, and the Cochrane Library databases for studies that compared micro-pulse and traditional CW-CPC in terms of their efficacy and safety profiles. We employed medical subject headings terms and keywords such as “cyclophotocoagulation,” “cyclodestructive,” “photocoagulation,” “CPC,” “micropulse,” “micro-pulse,” and “glaucoma” within the timeframe from 2015 to 2023. We assessed the success rate, IOP reduction, antiglaucoma medications, and complications of MP-CPC and CW-CPC. Results: We included six articles in this study, comprising two randomized controlled trials, three retrospective, and one prospective cohort, published between 2015 and 2023. Five out of six reported a significant reduction in IOP for both procedures with comparable success rates observed in MP-CPC compared to CW-CPC. One article reported an increase in IOP in MP-CPC. Both groups reported a decrease in the number of antiglaucoma medications, while one study reported an increase in medications in both MP-CPC and CW-CPC groups. Complication rates were lower in the MP-CPC group with two articles reporting a significant decrease compared to the CW-CPC group. Conclusion: MP-CPC has shown promising results in the treatment of glaucoma in the adult population. With comparable results in IOP reduction and fewer instances of serious ocular complications, MP-CPC may open new possibilities for the use of cyclophotocoagulation procedures in the earlier stages of glaucoma. However, its efficacy in the pediatric population and for neovascular glaucoma remains less defined, thus warranting further studies to establish optimal laser parameters for different types of glaucoma and specific populations of glaucoma patients.

Dear Colleagues, It is my great pleasure to introduce the first issue of the “Journal of the Turkish-German Gynecological Association (J Turk Ger Gynecol Assoc)” in the publishing year of 2022. This issue is consisted of seven articles and one review that we hope you will read with interest. Here we share some of our favorite articles that were published in this issue of the journal.

Dear Colleagues, It is my great pleasure to introduce the second issue of the “Journal of the Turkish-German Gynecological Association (J Turk Ger Gynecol Assoc)” in the publishing year of 2022. This issue is consisted of seven articles and one review that we hope you will read with interest. Here we share some of our favorite articles that were published in this issue of the journal.

I am delighted to introduce the first issue of the “Journal of the Turkish-German Gynecological Association (J Turk Ger Gynecol Assoc)” in the publishing year of 2021. This first issue of year 2021 contains articles on subjects of obstetrics, oncology, gynecology and infertility. As you know, telemedicine refers to the practice of caring for patients remotely when the doctor and patient are not physically present with each other. Modern technology has enabled doctors to consult patients by using video-conferencing tools. Here you will read a paper evaluating the feasibility of telephone interviews for patients in which non-urgent, conventional, post-operative check-up was suspended due to Coronavirus disease-2019 (COVID-19).

Objective: Catechol-O-methyltransferase (COMT), the product of the COMT gene, detoxifies the carcinogenic catechol estrogens. The aim of the present study was to examine the relationship between COMT Val158Met polymorphism and the risk of ovarian cancer. Material and Methods: The study groups consist of 94 individuals as a patients group with ovarian cancer (n=47) and control group (n=47). The allele and genotype frequencies were determined according to Hardy-Weinberg equilibrium (HWE). The allele and genotype frequencies. determined according to HWE. Genetic analysis were performed by real-time-polymerase chain reaction instrument, and the statistical analysis were performed by SPSS program. Results: Although no significant relationship was obtained among groups (p=0.413) regarding COMT gene Val158Met polymorphism, the genotype frequencies for COMT Val158Met (rs4860) polymorphism in groups was homozygote wild type GG genotype 25.5%, heterozygote GA genotype 46.8%, homozygote mutant AA genotype 27.7%. Conclusion: This study is the first to investigate the relationship between ovarian cancer and the Val158Met polymorphism in the COMT gene in a Turkish population. No statistically significant relationship was identified among genotypes belonging to the patient and control groups although sample sizes were relatively small and the analysis should be repeated in a larger cohort.