Journal Article

False-negative contrast-enhanced spectral mammography: use of more than one imaging modality and application of the triple test avoids misdiagnosis

O'Hanlon, Susan, Taylor, Donna, Latham, Bruce

2017

نظرة عامة

A 50-year-old woman presented with chest tenderness. On examination, both breasts were lumpy. Bilateral mammography showed heterogeneously dense parenchyma, with possible stromal distortion laterally on the right at the 0900 position. On ultrasound (US), a corresponding 13×9×10 mm irregular hypoechoic mass with internal vascularity was noted and both breasts had a complex heterogeneous fibroglandular background pattern. US-guided core biopsy with marker clip insertion was performed with the diagnosis of a grade 2 invasive ductal carcinoma (IDC). In view of the parenchymal pattern on mammography and US, contrast-enhanced spectral mammography (CESM) was performed for local staging. Mild background enhancement was noted, but there was no enhancement at the lesion site. The patient elected to have bilateral mastectomies and sentinel node biopsies. Final histopathology showed a node negative 11 mm grade 2 oestrogen and progesterone receptor positive, IDC.

• الناشر: BMJ Publishing Group LTD,BMJ Publishing Group
• موضوع: Australasia / Biopsy / Biopsy, Large-Core Needle / Breast - diagnostic imaging / Breast - pathology / Breast - surgery / Breast Density / Breast Neoplasms - diagnosis / Breasts / Carcinoma, Ductal, Breast - diagnosis / Carcinoma, Ductal, Breast - surgery / Contrast Media / Diagnostic Errors / Elective Surgical Procedures / Female / Humans / Mammography / Mastectomy / Middle Aged / Multimodal Imaging / Novel Diagnostic Procedure / Sensitivity and Specificity / Ultrasonography, Mammary - methods / White / Womens health